1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-diyl diacetate

• 常用名: 1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-diyl diacetate
• 英文名: 1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-diyl diacetate
• CAS号: 1269839-26-0
• 分子量: 416.464
• 密度: 1.2±0.1 g/cm3
• 沸点: 608.9±55.0 °C at 760 mmHg
• 分子式: C₂₃H₂₈O₇
• 熔点: N/A
• 闪点: 206.8±25.0 °C

用途

(3R,5R)-3,5-二乙酰氧基-1-(3,4-二羟基苯基)-7-(4-羟基苯基)庚烷,一种从姜黄根茎中提取的二芳基庚烷,具有多种生物和药理活性,包括抗氧化、抗肝毒性、抗炎、抗增殖、止吐和抗肿瘤活性[1]。

名称

• 中文名: 4-[(3R,5R)-3,5-二(乙酰氧基)-7-(4-羟基苯基)庚基]-1,2-苯二酚
• 英文名: 1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-diyl diacetate

生物活性

• 描述: (3R,5R)-3,5-二乙酰氧基-1-(3,4-二羟基苯基)-7-(4-羟基苯基)庚烷,一种从姜黄根茎中提取的二芳基庚烷,具有多种生物和药理活性,包括抗氧化、抗肝毒性、抗炎、抗增殖、止吐和抗肿瘤活性[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Shao-Dan Chen, et al. Five new diarylheptanoids from the rhizomes of Curcuma kwangsiensis and their antiproliferative activity. Fitoterapia. 2015 Apr;102:67-73.

物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 608.9±55.0 °C at 760 mmHg
• 分子式: C₂₃H₂₈O₇
• 分子量: 416.464
• 闪点: 206.8±25.0 °C
• 精确质量: 416.183502
• PSA: 113.29000
• LogP: 3.31
• InChIKey: PBCHINDGXDDCEA-UHFFFAOYSA-N
• SMILES: CC(=O)OC(CCc1ccc(O)cc1)CC(CCc1ccc(O)c(O)c1)OC(C)=O
• 外观性状: 油状物质
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.579
• 储存条件: 室温

靶点实验

查看更多实验

实验名称：Cytotoxicity against mouse RAW264.7 cells at 100 uM after 24 hrs by MTT assay 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL1826291

实验名称：Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells after 24 hr... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL1826290

实验名称：Cytotoxicity against mouse B16-4A5 cells assessed as cell viability at 10 uM after 70... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2427905

实验名称：Inhibition of mushroom tyrosinase at 10 uM 来源：ChEMBL 靶标：Polyphenol oxidase 2 External Id：CHEMBL2427904

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427909

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427908

实验名称：Cytotoxicity against mouse B16-4A5 cells assessed as cell viability at 3 uM after 70 ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2427906

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427912

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427911

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427910

共10条，当前第1页，共1页

1

英文别名

• (3R,5R)-1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)-3,5-heptanediyl diacetate