(4S,4aR,7S,7aR,12bS,13S)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9,13-triol结构式
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常用名 | (4S,4aR,7S,7aR,12bS,13S)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9,13-triol | 英文名 | (4S,4aR,7S,7aR,12bS,13S)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9,13-triol |
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| CAS号 | 131563-73-0 | 分子量 | 301.33700 | |
| 密度 | 1.54g/cm3 | 沸点 | 537.2ºC at 760mmHg | |
| 分子式 | C17H19NO4 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 278.7ºC | |
| 符号 |
GHS02, GHS06, GHS08 |
信号词 | Danger |
| 英文名 | (4S,4aR,7S,7aR,12bS,13S)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9,13-triol |
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| 英文别名 | 更多 |
| 密度 | 1.54g/cm3 |
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| 沸点 | 537.2ºC at 760mmHg |
| 分子式 | C17H19NO4 |
| 分子量 | 301.33700 |
| 闪点 | 278.7ºC |
| 精确质量 | 301.13100 |
| PSA | 73.16000 |
| LogP | 0.62690 |
| InChIKey | ISVKWTNAIRJURI-NGQSNTBFSA-N |
| SMILES | CN1CCC23c4c5ccc(O)c4OC2C(O)C=CC3C1C5O |
| 蒸汽压 | 2.27E-12mmHg at 25°C |
| 折射率 | 1.747 |
| 符号 |
GHS02, GHS06, GHS08 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H225-H301 + H311 + H331-H370 |
| 警示性声明 | P210-P260-P280-P301 + P310-P311 |
| 危险品运输编码 | UN1230 - class 3 - PG 2 - Methanol, solution |
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Impurities in a morphine sulfate drug product identified as 5-(hydroxymethyl)-2-furfural, 10-hydroxymorphine and 10-oxomorphine.
J. Pharm. Sci. 92(3) , 485-93, (2003) Stability testing of morphine sulfate formulated with nonpareil sugar seeds (consisting of sucrose and starch) and fumaric acid revealed the formation of the three impurities 5-(hydroxymethyl)-2-furfu... |
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Morphine impurity with opioid activity is identified as 10 alpha-hydroxymorphine.
Pharm. Res. 7(11) , 1205-7, (1990)
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Separation of morphine and its oxidation products by capillary zone electrophoresis.
J. Pharm. Biomed. Anal. 20(1-2) , 179-83, (1999) Separation of morphine and its oxidation products (10-S-hydroxymorphine, pseudomorphine and morphine N-oxide) by capillary zone electrophoresis in Tris-borate buffer in the presence of cyclodextrins w... |
| 10-Hydroxymorphine |