BMY-43748

• 常用名: BMY-43748
• 英文名: BMY-43748
• CAS号: 132195-65-4
• 分子量: 418.369
• 密度: 1.5±0.1 g/cm3
• 沸点: 661.0±55.0 °C at 760 mmHg
• 分子式: C₂₀H₁₇F₃N₄O₃
• 熔点: N/A
• 闪点: 353.6±31.5 °C

BMY-43748用途

BMY-43748 是一种抗菌剂，表现出很高的体内、体外抗菌活性。

BMY-43748名称

• 中文名: BMY-43748
• 英文名: BMY-43748

BMY-43748生物活性

• 描述: BMY-43748 是一种抗菌剂,表现出很高的体内、体外抗菌活性。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染
• 参考文献:

  [1]. J.-F.Dauphin, et al. Comparative metabolism of tosufloxacin and BMY 43748 in hepatocytes from rat, dog, monkey and man

BMY-43748物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 661.0±55.0 °C at 760 mmHg
• 分子式: C₂₀H₁₇F₃N₄O₃
• 分子量: 418.369
• 闪点: 353.6±31.5 °C
• 精确质量: 418.125275
• LogP: 1.67
• InChIKey: SKYPQEVVXGJKIJ-NSHDSACASA-N
• SMILES: Cc1c(F)c(N2CCC(N)C2)nc2c1c(=O)c(C(=O)O)cn2-c1ccc(F)cc1F
• 蒸汽压: 0.0±2.1 mmHg at 25°C
• 折射率: 1.637
• 储存条件: -20°C，密闭，干燥

BMY-43748靶点实验

查看更多实验

实验名称：% dose recovered in mouse urine 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL638288

实验名称：AUC in mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL622744

实验名称：In vitro for antibacterial activity against Morganella morganii 来源：ChEMBL 靶标：Morganella morganii External Id：CHEMBL732148

实验名称：Lethal dose was determined in OF1-strain female Swiss mice after intra venous adminis... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL741651

实验名称：Lethal dose was determined in OF1-strain female Swiss mice after oral administration ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL741652

实验名称：Cmax in mouse plasma 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL627045

实验名称：Compound was tested for acute toxicity against Pseudomonas aeruginosa A 9843 after or... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL764916

实验名称：In vitro for antibacterial activity against Klebsiella pneumoniae 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL704960

实验名称：Compound was tested for acute toxicity against Staphylococcus aureus A 15090 after or... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL807463

实验名称：In vitro for antibacterial activity against Bacillus fragilis. 来源：ChEMBL 靶标：Bacteroides fragilis External Id：CHEMBL649471

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BMY-43748英文别名

• 7-[(3S)-3-Amino-1-pyrrolidinyl]-1-(2,4-difluorophenyl)-6-fluoro-5-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
• 7-[(3S)-3-aminopyrrolidin-1-yl]-1-(2,4-difluorophenyl)-6-fluoro-5-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid