2-[2-(5-溴-1H-吲哚-3-基)乙基]-3-[3-(1-甲基乙氧基)苯基]-4-(3H-)-喹唑啉酮

• 常用名: 2-[2-(5-溴-1H-吲哚-3-基)乙基]-3-[3-(1-甲基乙氧基)苯基]-4-(3H-)-喹唑啉酮
• 英文名: LY 225910
• CAS号: 133040-77-4
• 分子量: 502.40200
• 密度: 1.39g/cm3
• 沸点: 690.3ºC at 760mmHg
• 分子式: C₂₇H₂₄BrN₃O₂
• 熔点: N/A
• 闪点: 371.3ºC
• 符号: GHS06
• 信号词: Danger

名称

• 中文名: 2-[2-(5-溴-1H-吲哚-3-基)乙基]-3-[3-(1-甲基乙氧基)苯基]-4-(3H-)-喹唑啉酮
• 英文名: 2-[2-(5-bromo-1H-indol-3-yl)ethyl]-3-(3-propan-2-yloxyphenyl)quinazolin-4-one

物理化学性质

• 密度: 1.39g/cm3
• 沸点: 690.3ºC at 760mmHg
• 分子式: C₂₇H₂₄BrN₃O₂
• 分子量: 502.40200
• 闪点: 371.3ºC
• 精确质量: 501.10500
• PSA: 59.91000
• LogP: 6.20190
• InChIKey: KUECXUACQOYKNB-UHFFFAOYSA-N
• SMILES: CC(C)Oc1cccc(-n2c(CCc3c[nH]c4ccc(Br)cc34)nc3ccccc3c2=O)c1
• 蒸汽压: 6.59E-19mmHg at 25°C
• 折射率: 1.667

安全信息

• 符号: GHS06
• 信号词: Danger
• 危害声明: H301-H413
• 警示性声明: P301 + P310
• 危险品运输编码: UN 2811 6.1 / PGIII

靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Inhibition of [125 I]CCK-8 binding to Cholecystokinin type B receptor of mouse cerebr... 来源：ChEMBL 靶标：Gastrin/cholecystokinin type B receptor External Id：CHEMBL662906

实验名称：Inhibition of [3H]-labeled L-364,718 binding to Cholecystokinin type A receptor in ra... 来源：ChEMBL 靶标：Cholecystokinin receptor type A External Id：CHEMBL659913

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Tocris HTS for Inhibitors of Aerobactin Synthetase lucA 来源：23265 External Id：IucA Pilot Assay Tocris Library

实验名称：qHTS for inhibitors of Vif-A3G interactions: Validation 来源：NCGC 靶标：DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] External Id：VIFG001

实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

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英文别名

• Tocris-1018
• 2-[2-(5-Bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy )phenyl]-4-(3H)-quinazolinone
• HMS3267O07