度鲁特韦中间体

• 常用名: 度鲁特韦中间体
• 英文名: (4R,12aS)-N-(2,4-Difluorobenzyl)-7-Methoxy-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxamide
• CAS号: 1335210-35-9
• 分子量: 433.405
• 密度: 1.5±0.1 g/cm3
• 沸点: 684.3±55.0 °C at 760 mmHg
• 分子式: C₂₁H₂₁F₂N₃O₅
• 熔点: N/A
• 闪点: 367.7±31.5 °C

度鲁特韦中间体名称

• 中文名: (4R,12aS)-N-((2,4-二氟苯基)甲基)-3,4,6,8,12,12a-六氢-7-甲氧基-4-甲基-6,8-二氧代-2H-吡啶并(1',2':4,5)吡嗪并(2,1-b)(1,3)恶嗪-9-甲酰胺
• 英文名: (4R,12aS)-N-(2,4-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
• 中文别名: 度鲁特韦中间体 | DOLUTEGRAVIR 中间体

度鲁特韦中间体物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 684.3±55.0 °C at 760 mmHg
• 分子式: C₂₁H₂₁F₂N₃O₅
• 分子量: 433.405
• 闪点: 367.7±31.5 °C
• 精确质量: 433.144928
• PSA: 89.87000
• LogP: -1.07
• 蒸汽压: 0.0±2.1 mmHg at 25°C
• 折射率: 1.618
• 储存条件: 室温，干燥密封

度鲁特韦中间体英文别名

• (4R,12aS)-N-(2,4-Difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
• (4R,12aS)-N-[[2,4-bis(fluoranyl)phenyl]methyl]-7-methoxy-4-methyl-6,8-bis(oxidanylidene)-3,4,12,12a-tetrahydro-2H-pyrido[5,6]pyrazino[2,6-b][1,3]oxazine-9-carboxamide
• 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-, (4R,12aS)-
• (4R,12aS)-N-(2,4-Difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxamide