纽莫康定 B0

• 常用名: 纽莫康定 B0
• 英文名: Pneumocandin B0
• CAS号: 135575-42-7
• 分子量: 1065.214
• 密度: 1.4±0.1 g/cm3
• 沸点: 1442.9±65.0 °C at 760 mmHg
• 分子式: C₅₀H₈₀N₈O₁₇
• 熔点: N/A
• 闪点: 826.5±34.3 °C

纽莫康定 B0用途

Pneumocandin B0(L-688786)是Cancidas的合成中间体。

纽莫康定 B0名称

• 中文名: 纽莫康定 B0
• 英文名: Pneumocandin B0
• 中文别名: 纽莫康定 | 纽莫康定B0(肺囊康定) | 纽莫康定B0((肺囊康定)

纽莫康定 B0生物活性

• 描述: Pneumocandin B0(L-688786)是Cancidas的合成中间体。
• 相关类别:
  信号通路 >> 抗感染 >> 真菌
  研究领域 >> 感染
• 参考文献:

  [1]. Welch CJ, et al. Preparation and evaluation of novel stationary phases for improved chromatographic purification of pneumocandin B0. J Chromatogr A. 2006 Jan 6;1101(1-2):204-13.

  [2]. Leonard WR Jr, et al. Synthesis of the antifungal beta-1,3-glucan synthase inhibitor CANCIDAS (caspofungin acetate) from pneumocandin B0. J Org Chem. 2007 Mar 30;72(7):2335-43.

纽莫康定 B0物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 1442.9±65.0 °C at 760 mmHg
• 分子式: C₅₀H₈₀N₈O₁₇
• 分子量: 1065.214
• 闪点: 826.5±34.3 °C
• 精确质量: 1064.564087
• PSA: 411.28000
• LogP: -5.00
• InChIKey: DQXPFAADCTZLNL-FXDJFZINSA-N
• SMILES: CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(O)C(O)NC(=O)C2C(O)CCN2C(=O)C(C(O)CC(N)=O)NC(=O)C(C(O)C(O)c2ccc(O)cc2)NC(=O)C2CC(O)CN2C(=O)C(C(C)O)NC1=O
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.630
• 储存条件: -20°C

纽莫康定 B0靶点实验

查看更多实验

实验名称：Antifungal activity against wild type Candida glabrata MY1381 assessed as growth inhi... 来源：ChEMBL 靶标：Nakaseomyces glabratus External Id：CHEMBL2389308

实验名称：Antifungal activity against wild type Candida lusitaniae MY1396 assessed as growth in... 来源：ChEMBL 靶标：Clavispora lusitaniae External Id：CHEMBL2389307

实验名称：Antifungal activity against wild type Candida krusei CLY549 assessed as growth inhibi... 来源：ChEMBL 靶标：Pichia kudriavzevii External Id：CHEMBL2389306

实验名称：Antifungal activity against wild type Candida parapsilosis ATCC 22019 assessed as gro... 来源：ChEMBL 靶标：Candida parapsilosis External Id：CHEMBL2389305

实验名称：Antifungal activity against wild type Candida albicans MY1055 assessed as growth inhi... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL2389310

实验名称：Antifungal activity against wild type Candida albicans MY1055 assessed as growth inhi... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL2389309

实验名称：Antifungal activity against Candida albicans CAI4-R1 assessed as growth inhibition af... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL2389300

实验名称：Antifungal activity against Candida albicans NR3 assessed as growth inhibition after ... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL2389103

实验名称：Antibacterial activity against methicillin-sensitive Staphylococcus aureus MB2865 ass... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL2389102

实验名称：Antibacterial activity against Escherichia coli ATCC 25922 assessed as growth inhibit... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL2389101

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纽莫康定 B0英文别名

• N-{(2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-[(1R)-3-Amino-1-hydroxy-3-oxopropyl]-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide
• PneumocandinB0
• B0 PneuMocandin B0
• pneumocandin Bo
• Pneumocardin B0