Antitubercular agent-39

• 常用名: Antitubercular agent-39
• 英文名: Antitubercular agent-39
• CAS号: 1357796-08-7
• 分子量: 430.54
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₃₀N₄O₂
• 熔点: N/A
• 闪点: N/A

Antitubercular agent-39用途

Antitubercular agent-39 (Compound P1) 是一种有效的抗结核剂。Antitubercular agent-39 对耐药菌株和药物敏感的临床分离株具有活性。Antitubercular agent-39 抑制 Mtb 菌株 H37Rv 的 MIC 小于 1 μM。

Antitubercular agent-39名称

• 英文名: Antitubercular agent-39

Antitubercular agent-39生物活性

• 描述: Antitubercular agent-39 (Compound P1) 是一种有效的抗结核剂。Antitubercular agent-39 对耐药菌株和药物敏感的临床分离株具有活性。Antitubercular agent-39 抑制 Mtb 菌株 H37Rv 的 MIC 小于 1 μM。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Veena D. Yadav, et al. Synthesis and Structure–Activity Relationships of a New Class of Oxadiazoles Targeting DprE1 as Antitubercular Agents. ACS Med. Chem. Lett. 2023, 14, 9, 1275-1283.

Antitubercular agent-39物理化学性质

• 分子式: C₂₆H₃₀N₄O₂
• 分子量: 430.54
• InChIKey: UBKCDMOSNZQGSX-UHFFFAOYSA-N
• SMILES: O=C(C1CCN(c2nnc(-c3ccccc3)o2)CC1)N1CCC(Cc2ccccc2)CC1

Antitubercular agent-39靶点实验

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实验名称：Antitubercular activity against Mycobacterium tuberculosis infected in mouse J774 cel... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL5372786

实验名称：Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incuba... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL5372784

实验名称：Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incuba... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL5372785

实验名称：Induction of DNA damage in Mycobacterium tuberculosis H37Rv transfected with PradA-LU... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL5372782

实验名称：Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed ... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL5372783

实验名称：Inhibition of DprE1-mediated cell wall synthesis in Mycobacterium tuberculosis H37Rv ... 来源：ChEMBL 靶标：Decaprenylphosphoryl-beta-D-ribose oxidase External Id：CHEMBL5372780

实验名称：Induction of DNA damage in Mycobacterium tuberculosis H37Rv transfected with PrecA-LU... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL5372781

实验名称：Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed ... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL5372776

实验名称：Alphascreen assay for small molecules abrogating mHTT-CaM Interaction 来源：24983 靶标：Huntingtin External Id：KUHTS-Muma KU-CaM-Htt INH-01

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