LY 274614

• 常用名: LY 274614
• 英文名: LY 274614
• CAS号: 136109-04-1
• 分子量: 277.25
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₁H₂₀NO₅P
• 熔点: N/A
• 闪点: N/A

LY 274614用途

LY 274614 是具有口服活性的竞争性 NMDA 受体拮抗剂。LY 274614 可用于神经系统疾病研究。

LY 274614名称

• 英文名: 6-(phosphonomethyl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid

LY 274614生物活性

• 描述: LY 274614 是具有口服活性的竞争性 NMDA 受体拮抗剂。LY 274614 可用于神经系统疾病研究。
• 相关类别:
  信号通路 >> 神经信号通路 >> iGluR
  研究领域 >> 神经疾病
  信号通路 >> 跨膜转运 >> iGluR
• 参考文献:

  [1]. Schoepp DD, et al. Neuroprotectant effects of LY274614, a structurally novel systemically active competitive NMDA receptor antagonist. J Neural Transm Gen Sect. 1991;85(2):131-143.

LY 274614物理化学性质

• 分子式: C₁₁H₂₀NO₅P
• 分子量: 277.25
• 精确质量: 277.10800
• PSA: 116.67000
• LogP: 0.97190
• 蒸汽压: 4.5E-13mmHg at 25°C

LY 274614靶点实验

查看更多实验

实验名称：qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1):... 来源：NCGC 靶标：thioredoxin reductase [Rattus norvegicus] External Id：TRXR101

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (E... 来源：NCGC External Id：epac1-activator-v

实验名称：Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3... 来源：NCGC External Id：epac1-inhibitor-v

实验名称：qHTS for Inhibitors of Polymerase Iota 来源：NCGC 靶标：DNA polymerase iota [Homo sapiens] External Id：PolI100

实验名称：Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (E... 来源：NCGC External Id：epac2-activator-v2

实验名称：Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4... 来源：NCGC External Id：epac2-inhibitor-v2

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：qHTS for Inhibitors of Polymerase Kappa 来源：NCGC 靶标：DNA polymerase kappa [Homo sapiens] External Id：PolK100

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LY 274614英文别名

• 6-(phosphonomethyl)decahydroisoquinoline-3-carboxylic acid
• (3S,4aR,6S,8aR)-6-(phosphonomethyl)decahydroisoquinoline-3-carboxylic acid
• 3-Isoquinolinecarboxylicacid,decahydro-6-(phosphonomethyl)-,(3S,4aR,6S,8aR)