钙蛋白酶抑制剂II(进口)

更新时间:2024-01-04 19:22:04

钙蛋白酶抑制剂II(进口)结构式
钙蛋白酶抑制剂II(进口)结构式
品牌特惠专场
常用名 钙蛋白酶抑制剂II(进口) 英文名 ALLM
CAS号 136632-32-1 分子量 401.564
密度 1.1±0.1 g/cm3 沸点 676.5±55.0 °C at 760 mmHg
分子式 C19H35N3O4S 熔点 N/A
MSDS 美版 闪点 362.9±31.5 °C

 钙蛋白酶抑制剂II(进口)用途


A potent, cell-permeable calpain inhibitor with Ki of 0.6 and 100 nM for calpain L and calpain B, respectively; inhibits the activities of Ca(2+)-dependent neutral proteases as well as lysosomal proteases, including cathepsin L, cathepsin B, and cathepsin D; induce apoptosis in rat pituitary tumor cells by specific caspase activation.

 钙蛋白酶抑制剂II(进口)名称

中文名 钙蛋白酶抑制剂II(进口)
英文名 N-Acetylleucyl-N-[4-(methylsulfanyl)-1-oxo-2-butanyl]leucinamide
英文别名 更多

 钙蛋白酶抑制剂II(进口)物理化学性质

密度 1.1±0.1 g/cm3
沸点 676.5±55.0 °C at 760 mmHg
分子式 C19H35N3O4S
分子量 401.564
闪点 362.9±31.5 °C
精确质量 401.234833
LogP 2.64
蒸汽压 0.0±2.1 mmHg at 25°C
折射率 1.496
储存条件

密封、在 -20ºC下保存

更多

1. 性状:未确定

2. 密度(g/mL,20℃):未确定

3. 相对蒸汽密度(g/mL,空气=1):未确定

4. 熔点(ºC):未确定

5. 沸点(ºC,常压):未确定

6. 沸点(ºC,KPa):未确定

7. 折射率:未确定

8. 闪点(ºC):未确定

9. 比旋光度(º):未确定

10. 自燃点或引燃温度(ºC):未确定

11. 蒸气压(Pa,20ºC):未确定

12. 饱和蒸气压(KPa,20ºC):未确定

13. 燃烧热(KJ/mol):未确定

14. 临界温度(ºC):未确定

15. 临界压力(KPa):未确定

16. 油水(辛醇/水)分配系数的对数值:未确定

17. 爆炸上限(%,V/V):未确定

18. 爆炸下限(%,V/V):未确定

19. 溶解性:未确定

 钙蛋白酶抑制剂II(进口)安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
安全声明 (欧洲) S22;S24/25
危险品运输编码 NONH for all modes of transport

 钙蛋白酶抑制剂II(进口)文献12

更多文献
Compartmentalization of the chick cerebellar cortex based on the link between the striped expression pattern of aldolase C and the topographic olivocerebellar projection.

J. Comp. Neurol. 523 , 1886-912, (2015)

The avian cerebellum is organized into multiple longitudinal stripes defined by expression profiles of aldolase C (zebrin II) in Purkinje cells. The relationship between the aldolase C striped pattern...

Targeting microparticle biogenesis: a novel approach to the circumvention of cancer multidrug resistance.

Curr. Cancer Drug Targets 15 , 205-14, (2015)

Microparticles (MPs) are released from most eukaryotic cells after the vesiculation of the plasma membrane and serve as vectors of long and short-range signaling. MPs derived from multidrug resistant ...

Increased μ-Calpain Activity in Blasts of Common B-Precursor Childhood Acute Lymphoblastic Leukemia Correlates with Their Lower Susceptibility to Apoptosis.

PLoS ONE 10 , e0136615, (2015)

Childhood acute lymphoblastic leukemia (ALL) blasts are characterized by inhibited apoptosis promoting fast disease progress. It is known that in chronic lymphocytic and acute myeloid leukemias the re...

 钙蛋白酶抑制剂II(进口)英文别名

N-Acetylleucyl-N-[4-(methylsulfanyl)-1-oxobutan-2-yl]leucinamide
Leucinamide, N-acetylleucyl-N-[1-formyl-3-(methylthio)propyl]-
N-Acetylleucyl-N-[4-(methylsulfanyl)-1-oxo-2-butanyl]leucinamide
MFCD00065506
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