印度榅桲素

• 常用名: 印度榅桲素
• 英文名: (±)-Marmesin
• CAS号: 13710-70-8
• 分子量: 246.259
• 密度: 1.3±0.1 g/cm3
• 沸点: 434.0±45.0 °C at 760 mmHg
• 分子式: C₁₄H₁₄O₄
• 熔点: N/A
• 闪点: 168.0±22.2 °C

印度榅桲素用途

(±)-马美辛是线性呋喃香豆素的良好前体。(±)-马来霉素衍生物具有高度的乙酰胆碱酯酶抑制性质[1][2]。

印度榅桲素名称

• 中文名: 印度榅桲素
• 英文名: marmesin

印度榅桲素生物活性

• 描述: (±)-马美辛是线性呋喃香豆素的良好前体。(±)-马来霉素衍生物具有高度的乙酰胆碱酯酶抑制性质[1][2]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 神经信号通路 >> 疼痛
• 靶点实验:

  AChE

• 参考文献:

  [1]. Austin D J, et al. Furanocoumarin biosynthesis in Ruta graveolens cell cultures[J]. Phytochemistry, 1973, 12(7): 1657-1667.

  [2]. Rao J M, et al. Pharmaceutical composition useful as acetylcholinesterase inhibitors: U.S. Patent 8,188,143[P]. 2012-5-29.

印度榅桲素物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 434.0±45.0 °C at 760 mmHg
• 分子式: C₁₄H₁₄O₄
• 分子量: 246.259
• 闪点: 168.0±22.2 °C
• 精确质量: 246.089203
• LogP: 1.69
• InChIKey: FWYSBEAFFPBAQU-UHFFFAOYSA-N
• SMILES: CC(C)(O)C1Cc2cc3ccc(=O)oc3cc2O1
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.611

印度榅桲素靶点实验

查看更多实验

实验名称：Cytotoxicity against human HepG2 cells at 10 uM 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4125397

实验名称：Cytoprotective activity against 100 uM t-BHP-induced oxidative stress in human HepG2 ... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4125398

实验名称：A screen for compounds that inhibit cell wall-associated teichoic acid synthesis in S... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS704

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：ORF 73 [Human herpesvirus 8 type M] External Id：HMS791

实验名称：High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS1303

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Inhibition of RAD52 (unknown origin) assessed as reduction in RAD52-ssDNA interaction... 来源：ChEMBL 靶标：DNA repair protein RAD52 homolog External Id：CHEMBL4482621

实验名称：A screen for compounds that inhibit viral RNA polymerase binding and polymerization a... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Chain A, Poliovirus Polymerase With Gtp External Id：HMS750

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印度榅桲素英文别名

• 2-(2-Hydroxy-2-propanyl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one
• marmesin
• 2-(2-hydroxypropan-2-yl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one
• 2-(1-Hydroxy-1-methyl-ethyl)-2,3-dihydro-furo[3,2-g]chromen-7-one
• 2-(1-Hydroxy-1-methylethyl)-2,3-dihydrofuro[3,2-g]chromen-7-one