Aptiganel hydrochloride

• 常用名: Aptiganel hydrochloride
• 英文名: Aptiganel hydrochloride
• CAS号: 137160-11-3
• 分子量: 303.401
• 密度: 1.1±0.1 g/cm3
• 沸点: 490.9±38.0 °C at 760 mmHg
• 分子式: C₂₀H₂₂ClN₃
• 熔点: N/A
• 闪点: 250.7±26.8 °C

Aptiganel hydrochloride用途

盐酸阿普甘奈尔(Cerestat)是一种具有神经保护作用的非竞争性NMDA受体拮抗剂。

Aptiganel hydrochloride名称

• 英文名: Aptiganel

Aptiganel hydrochloride生物活性

• 描述: 盐酸阿普甘奈尔(Cerestat)是一种具有神经保护作用的非竞争性NMDA受体拮抗剂。
• 相关类别:
  信号通路 >> 神经信号通路 >> iGluR
  研究领域 >> 神经疾病
  信号通路 >> 跨膜转运 >> iGluR
• 参考文献:

  [1]. Kroppenstedt SN, Schneider GH, Thomale UW, Unterberg AW. Neuroprotective properties of aptiganel HCL (Cerestat) following controlled cortical impact injury. Acta Neurochir Suppl. 1998;71:114-116.

  [2]. McBurney RN. Development of the NMDA ion-channel blocker, aptiganel hydrochloride, as a neuroprotective agent for acute CNS injury. Int Rev Neurobiol. 1997;40:173-195.

Aptiganel hydrochloride物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 490.9±38.0 °C at 760 mmHg
• 分子式: C₂₀H₂₂ClN₃
• 分子量: 303.401
• 闪点: 250.7±26.8 °C
• 精确质量: 303.173553
• LogP: 5.04
• InChIKey: CKAKVKWRMCAYJD-UHFFFAOYSA-N
• SMILES: CCc1cccc(N(C)C(N)=Nc2cccc3ccccc23)c1.Cl
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.600

Aptiganel hydrochloride靶点实验

查看更多实验

实验名称：Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL1266185

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity 来源：NCGC External Id：HERG01

实验名称：qHTS for Inhibitors of TGF-b: Cytotox Counterscreen 来源：NCGC 靶标：N/A External Id：SMAD3201

实验名称：uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay 来源：Burnham Center for Chemical Genomics 靶标：cystic fibrosis transmembrane conductance regulator [Homo sapiens] External Id：SBCCG-A764-CF-PAF-Primary-Assay

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ant... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_ANT_FLUO8_1536_1X%INH PRUN

实验名称：qHTS for Inhibitors of TGF-b 来源：NCGC 靶标：Smad3 [Homo sapiens] External Id：SMAD3101

共400条，当前第1页，共40页

1

2

3

4

5

Aptiganel hydrochloride英文别名

• 1-(3-ethylphenyl)-1-methyl-3-naphthalen-1-ylguanidine
• 1-(3-Ethylphenyl)-1-methyl-2-(1-naphthyl)guanidine
• N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine
• 46475LV84I
• Aptiganel