Nivasorexant

• 常用名: Nivasorexant
• 英文名: Nivasorexant
• CAS号: 1435480-40-2
• 分子量: 429.47
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₃N₇O₂
• 熔点: N/A
• 闪点: N/A

Nivasorexant用途

Nivasorexant是一种有效的食欲素受体拮抗剂[1]。

Nivasorexant名称

• 英文名: Nivasorexant

Nivasorexant生物活性

• 描述: Nivasorexant是一种有效的食欲素受体拮抗剂[1]。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 食欲素受体(OX受体)
  研究领域 >> 神经疾病
• 参考文献:

  [1]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical

Nivasorexant物理化学性质

• 分子式: C₂₃H₂₃N₇O₂
• 分子量: 429.47
• InChIKey: GKPHAIOJCHBZCT-HXUWFJFHSA-N
• SMILES: Cc1ccc(C(=O)N2CCOCC2Cc2cccc(-n3nccn3)c2)c(-n2nccn2)c1

Nivasorexant靶点实验

查看更多实验

实验名称：Unbound drug concentration in Wistar rat brain at 1 mg/kg, po measured after 1 hr by ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541950

实验名称：Drug concentration in cerebrospinal fluid of Wistar rat at 1 mg/kg, po measured after... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541951

实验名称：Ratio of unbound drug concentration in Wistar rat brain to plasma at 1 mg/kg, po meas... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541952

实验名称：In vivo receptor occupancy at OX1R in Wistar rat brain at 1 mg/kg, po measured after ... 来源：ChEMBL 靶标：Orexin/Hypocretin receptor type 1 External Id：CHEMBL5541953

实验名称：Solubility of compound in FeSSIF 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541954

实验名称：Selectivity ratio of appKb for human OX2R expressed in CHO cells to appKb for human O... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541957

实验名称：Selectivity ratio of appKb for rat OX2R expressed in CHO cells to appKb for rat OX1R ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541960

实验名称：In vivo receptor occupancy at OX1R in Wistar rat brain at 30 mg/kg, po measured after... 来源：ChEMBL 靶标：Orexin/Hypocretin receptor type 1 External Id：CHEMBL5541963

实验名称：In vivo receptor occupancy at OX2R in Wistar rat brain at 30 mg/kg, po measured after... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541964

实验名称：In vivo receptor occupancy at OX1R in Wistar rat brain at 100 mg/kg, po measured afte... 来源：ChEMBL 靶标：Orexin/Hypocretin receptor type 1 External Id：CHEMBL5541967

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