GSK2838232

• 常用名: GSK2838232
• 英文名: GSK-2838232
• CAS号: 1443460-91-0
• 分子量: 809.556
• 密度: 1.2±0.1 g/cm3
• 沸点: 817.1±65.0 °C at 760 mmHg
• 分子式: C₄₈H₇₃ClN₂O₆
• 熔点: N/A
• 闪点: 448.0±34.3 °C

GSK2838232用途

GSK2838232 抑制HIV逆转录酶活性, 详细信息请参考专利文献WO/2013090664A1中的化合物51。

GSK2838232名称

• 中文名: GSK2838232
• 英文名: GSK2838232

GSK2838232生物活性

• 描述: GSK2838232 抑制HIV逆转录酶活性, 详细信息请参考专利文献WO/2013090664A1中的化合物51。
• 相关类别:
  信号通路 >> 抗感染 >> HIV
  研究领域 >> 感染
• 参考文献:

  [1]. Hatcher Mark Andrew, et al. Preparation of betulin derivatives for the treatment of HIV. From PCT Int. Appl. (2013), WO 2013090664 A1 20130620.

GSK2838232物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 817.1±65.0 °C at 760 mmHg
• 分子式: C₄₈H₇₃ClN₂O₆
• 分子量: 809.556
• 闪点: 448.0±34.3 °C
• 精确质量: 808.515686
• LogP: 11.63
• InChIKey: MEOWKUXNVNJAMY-PZFKGGKESA-N
• SMILES: CC(C)C1=C2C3CCC4C5(C)CCC(OC(=O)CC(C)(C)C(=O)O)C(C)(C)C5CCC4(C)C3(C)CCC2(C(O)CN(CCN(C)C)Cc2ccc(Cl)cc2)CC1=O
• 蒸汽压: 0.0±3.1 mmHg at 25°C
• 折射率: 1.577
• 储存条件: 2-8℃

GSK2838232靶点实验

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实验名称：NCATS anti-infectives library activity on HEK293 viability as a counter-qHTS vs the C... 来源：NCGC 靶标：N/A External Id：adst_HEK293_Anti-infectives-02

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808149

实验名称：NCATS anti-infectives library activity on the primary C. elegans qHTS viability assay 来源：NCGC 靶标：N/A External Id：adst_Celegans_Anti-infectives-o1

实验名称：Enzymatic assay of human HDAC6 with custom peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808150

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4513082

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4303805

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：MT4 Cell Antiviral Assay from US Patent US10064873: "Compounds and compositions for t... 来源：BindingDB 靶标：N/A External Id：BindingDB_478_1

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

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GSK2838232英文别名

• G9C7884M8M
• GSK-2838232