DGAT1-IN-1

• 常用名: DGAT1-IN-1
• 英文名: DGAT1-IN-1
• CAS号: 1449779-49-0
• 分子量: 551.556
• 密度: 1.4±0.1 g/cm3
• 沸点: N/A
• 分子式: C₃₀H₂₈F₃N₃O₄
• 熔点: N/A
• 闪点: N/A

DGAT1-IN-1用途

DGAT1-IN-1是高效DGAT1抑制剂，IC50值低于10nM（Hep3B细胞过表达DGAT1裂解物测得）。

DGAT1-IN-1名称

• 中文名: DGAT1-IN-1
• 英文名: {trans-4-[4-(2-{[4-(Trifluoromethoxy)benzyl]carbamoyl}imidazo[1,2-a]pyridin-6-yl)phenyl]cyclohexyl}acetic acid

DGAT1-IN-1生物活性

• 描述: DGAT1-IN-1是高效DGAT1抑制剂,IC50值低于10nM(Hep3B细胞过表达DGAT1裂解物测得)。
• 相关类别:
  信号通路 >> 代谢酶/蛋白酶 >> 酰基转移酶
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme , Patent: WO 2013119040 A1

DGAT1-IN-1物理化学性质

• 密度: 1.4±0.1 g/cm3
• 分子式: C₃₀H₂₈F₃N₃O₄
• 分子量: 551.556
• 精确质量: 551.203186
• LogP: 6.92
• InChIKey: KFGSQOIWOCDWAS-UHFFFAOYSA-N
• SMILES: O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)NCc5ccc(OC(F)(F)F)cc5)cn4c3)cc2)CC1
• 折射率: 1.620
• 储存条件: 2-8℃

DGAT1-IN-1靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ... 来源：NCGC External Id：s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

实验名称：Cytochrome P450 family 3 subfamily A member 7 (CYP3A7) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A7681

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DGAT1-IN-1英文别名

• {trans-4-[4-(2-{[4-(Trifluoromethoxy)benzyl]carbamoyl}imidazo[1,2-a]pyridin-6-yl)phenyl]cyclohexyl}acetic acid
• DGAT1-IN-1