DGAT1-IN-1

Modify Date: 2024-01-05 15:54:52

DGAT1-IN-1 Structure
DGAT1-IN-1 structure
Common Name DGAT1-IN-1
CAS Number 1449779-49-0 Molecular Weight 551.556
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C30H28F3N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DGAT1-IN-1


DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1).IC50 value: < 10 nMTarget: DGAT1 inhibitorImidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparationBy Kim, Dooseop; Bok, Juhan; Shin, Sunmi From PCT Int. Appl. (2013), WO 2013119040 A1 20130815.

 Names

Name {trans-4-[4-(2-{[4-(Trifluoromethoxy)benzyl]carbamoyl}imidazo[1,2-a]pyridin-6-yl)phenyl]cyclohexyl}acetic acid
Synonym More Synonyms

 DGAT1-IN-1 Biological Activity

Description DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1).IC50 value: < 10 nMTarget: DGAT1 inhibitorImidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparationBy Kim, Dooseop; Bok, Juhan; Shin, Sunmi From PCT Int. Appl. (2013), WO 2013119040 A1 20130815.
Related Catalog
References

[1]. Compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme , Patent: WO 2013119040 A1

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C30H28F3N3O4
Molecular Weight 551.556
Exact Mass 551.203186
LogP 6.92
Index of Refraction 1.620
Storage condition 2-8℃

 Synonyms

{trans-4-[4-(2-{[4-(Trifluoromethoxy)benzyl]carbamoyl}imidazo[1,2-a]pyridin-6-yl)phenyl]cyclohexyl}acetic acid
Cyclohexaneacetic acid, 4-[4-[2-[[[[4-(trifluoromethoxy)phenyl]methyl]amino]carbonyl]imidazo[1,2-a]pyridin-6-yl]phenyl]-, trans-
DGAT1-IN-1
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