(3R,5S)-REL-1-(4-羟基-3,5-二甲氧基苯基)-7-(4-羟基苯基)-3,5-庚二醇

• 常用名: (3R,5S)-REL-1-(4-羟基-3,5-二甲氧基苯基)-7-(4-羟基苯基)-3,5-庚二醇
• 英文名: Diarylcomosol III
• CAS号: 1452487-93-2
• 分子量: 376.44
• 密度: 1.2±0.1 g/cm3
• 沸点: 623.5±55.0 °C at 760 mmHg
• 分子式: C₂₁H₂₈O₆
• 熔点: N/A
• 闪点: 330.9±31.5 °C

用途

二芳基共聚溶胶III是一种二芳基庚烷类化合物,可以从姜黄的干燥根茎中分离出来。姜黄的根茎具有芳香健胃和抗炎活性[1]。

名称

• 中文名: (3R,5S)-REL-1-(4-羟基-3,5-二甲氧基苯基)-7-(4-羟基苯基)-3,5-庚二醇
• 英文名: (3R,5S)-1-(4-Hydroxy-3,5-dimethoxyphenyl)-7-(4-hydroxyphenyl)-3,5-heptanediol

生物活性

• 描述: 二芳基共聚溶胶III是一种二芳基庚烷类化合物,可以从姜黄的干燥根茎中分离出来。姜黄的根茎具有芳香健胃和抗炎活性[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Matsumoto T, et al. Diarylheptanoids with inhibitory effects on melanogenesis from the rhizomes of Curcuma comosa in B16 melanoma cells. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5178-81.

物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 623.5±55.0 °C at 760 mmHg
• 分子式: C₂₁H₂₈O₆
• 分子量: 376.44
• 闪点: 330.9±31.5 °C
• 精确质量: 376.188599
• LogP: 1.61
• InChIKey: OJGXSPXNGOVDNO-ZWKOTPCHSA-N
• SMILES: COc1cc(CCC(O)CC(O)CCc2ccc(O)cc2)cc(OC)c1O
• 外观性状: 粉末
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.592
• 储存条件: 2-8℃

安全信息

• 危害码 (欧洲): Xi

靶点实验

查看更多实验

实验名称：Cytotoxicity against mouse B16-4A5 cells assessed as cell viability at 10 uM after 70... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2427905

实验名称：Inhibition of mushroom tyrosinase at 10 uM 来源：ChEMBL 靶标：Polyphenol oxidase 2 External Id：CHEMBL2427904

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427909

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427908

实验名称：Inhibition of urease (unknown origin) using urea as substrate preincubated for 30 min... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5337965

实验名称：Cytotoxicity against mouse B16-4A5 cells assessed as cell viability at 3 uM after 70 ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2427906

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427912

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427911

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427910

共9条，当前第1页，共1页

1

英文别名

• (3R,5S)-1-(4-Hydroxy-3,5-dimethoxyphenyl)-7-(4-hydroxyphenyl)-3,5-heptanediol