N-甲基衡州乌药碱

• 常用名: N-甲基衡州乌药碱
• 英文名: N-Methylcoclaurine
• CAS号: 1472-62-4
• 分子量: 299.36
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₂₁NO₃
• 熔点: N/A
• 闪点: N/A

N-甲基衡州乌药碱用途

(±)-N-甲基椰油酰胺是一种选择性α2-肾上腺素受体拮抗剂[1]。

N-甲基衡州乌药碱名称

• 中文名: N-甲基衡州乌药碱
• 英文名: (+/-)-N-methyl coclaurine

N-甲基衡州乌药碱生物活性

• 描述: (±)-N-甲基椰油酰胺是一种选择性α2-肾上腺素受体拮抗剂[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体
• 参考文献:

  [1]. H H Pauli, et al. Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis. Plant J. 1998 Mar;13(6):793-801.

N-甲基衡州乌药碱物理化学性质

• 分子式: C₁₈H₂₁NO₃
• 分子量: 299.36
• 精确质量: 299.15200
• PSA: 52.93000
• LogP: 2.81600
• InChIKey: BOKVLBSSPUTWLV-UHFFFAOYSA-N
• SMILES: COc1cc2c(cc1O)C(Cc1ccc(O)cc1)N(C)CC2

N-甲基衡州乌药碱靶点实验

查看更多实验

实验名称：Inhibition of arachidonic acid-induced platelet aggregation in rabbit platelet-rich p... 来源：ChEMBL 靶标：Platelet External Id：CHEMBL987624

实验名称：Inhibition of adenosine diphosphate-induced platelet aggregation in rabbit platelet-r... 来源：ChEMBL 靶标：Platelet External Id：CHEMBL987621

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar... 来源：NCGC 靶标：67.9K protein [Vaccinia virus] External Id：Vaccinia-p2mCherry

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：Vasorelaxant activity against high potassium-induced contraction in Wistar rat thorac... 来源：ChEMBL 靶标：Aorta External Id：CHEMBL990267

实验名称：Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimo... 来源：ChEMBL 靶标：Solute carrier organic anion transporter family member 1B3 External Id：CHEMBL3039491

实验名称：The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre... 来源：11924 靶标：N/A External Id：CGM data for Cell Systems paper Dec 2015

实验名称：Inhibition of collagen-induced platelet aggregation in rabbit platelet-rich plasma at... 来源：ChEMBL 靶标：Platelet External Id：CHEMBL987627

实验名称：qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary ... 来源：NCGC 靶标：67.9K protein [Vaccinia virus] External Id：Vaccinia-p2Venus

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N-甲基衡州乌药碱英文别名

• (+/-)-N-methylcoclaurine
• 1-(4-hydroxy-benzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-7-ol
• (+/-)-1-(4-Hydroxy-benzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydro-isochinolin-7-ol
• rac-N-Methyl-coclaurin,(+/-)-1-(p-Hydroxy-benzyl)-2-methyl-6-methoxy-7-hydroxy-1,2,3,4-tetrahydro-isochinolin