PGN36

• 常用名: PGN36
• 英文名: PGN36
• CAS号: 1564253-75-3
• 分子量: 365.43
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₃N₃O₃
• 熔点: N/A
• 闪点: N/A

PGN36用途

PGN36(化合物18)是一种选择性大麻素CB2受体(CB2R)拮抗剂,Ki为0.09µM【1】。

PGN36名称

• 英文名: PGN36

PGN36生物活性

• 描述: PGN36(化合物18)是一种选择性大麻素CB2受体(CB2R)拮抗剂,Ki为0.09µM【1】。
• 相关类别:
  研究领域 >> 炎症/免疫
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 大麻素受体
• 靶点实验:

  cannabinoid type-2 receptors:0.09 μM (Ki)

• 参考文献:

  [1]. González-Naranjo P, et al. New cannabinoid receptor antagonists as pharmacological tool. Bioorg Med Chem. 2020 Oct 1;28(19):115672.

PGN36物理化学性质

• 分子式: C₂₁H₂₃N₃O₃
• 分子量: 365.43

PGN36靶点实验

查看更多实验

实验名称：Cytotoxicity against mouse MC3T3-E1 cell assessed as reduction in cell viability at 1... 来源：ChEMBL 靶标：MC3T3-E1 External Id：CHEMBL4730273

实验名称：Agonist activity at CB2 receptor in mouse MC3T3-E1 cells assessed as induction of bon... 来源：ChEMBL 靶标：Cannabinoid receptor 2 External Id：CHEMBL4730274

实验名称：Displacement of [3H]CP55940 from human CB2R transfected in HEK293EBNA cell membrane i... 来源：ChEMBL 靶标：Cannabinoid receptor 2 External Id：CHEMBL4730271

实验名称：Selectivity index, ratio of Ki for human CB1R transfected in HEK293EBNA cell membrane... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4730272

实验名称：Antagonist activity at cannabinoid receptor in ICR mouse vas deferens assessed as red... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4730277

实验名称：Inverse agonist activity at cannabinoid receptor in ICR mouse vas deferens assessed a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4730278

实验名称：Inhibition of human BuChE using butyrylthiocholine as substrate by Ellman's method 来源：ChEMBL 靶标：Cholinesterase External Id：CHEMBL3119241

实验名称：Antagonist activity at CB2 receptor in mouse MC3T3-E1 cells assessed as inhibition of... 来源：ChEMBL 靶标：Cannabinoid receptor 2 External Id：CHEMBL4730275

实验名称：Inhibition of horse serum BuChE using butyrylthiocholine as substrate by Ellman's met... 来源：ChEMBL 靶标：Cholinesterase External Id：CHEMBL3119242

实验名称：Displacement of [3H]CP55940 from human CB1R transfected in HEK293EBNA cell membrane i... 来源：ChEMBL 靶标：Cannabinoid receptor 1 External Id：CHEMBL4730276

共14条，当前第1页，共2页

1

2