F-17

• 常用名: F-17
• 英文名: F-17
• CAS号: 1572464-22-2
• 分子量: 363.20
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₅BrO₄
• 熔点: N/A
• 闪点: N/A

F-17用途

F-17是一种潜在的毒力因子抑制剂。F-17对生物膜、弹性蛋白酶、绿脓杆菌素和群集运动有非常显著的抑制作用。F-17对LasR和PqsR也有良好的结合作用。F-17没有明显的细胞毒性[1]。

F-17名称

• 英文名: F-17

F-17生物活性

• 描述: F-17是一种潜在的毒力因子抑制剂。F-17对生物膜、弹性蛋白酶、绿脓杆菌素和群集运动有非常显著的抑制作用。F-17对LasR和PqsR也有良好的结合作用。F-17没有明显的细胞毒性[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Yun-feng Zeng, et al. Design and synthesis of caffeic acid derivatives and evaluation of their inhibitory activity against Pseudomonas aeruginosa.

F-17物理化学性质

• 分子式: C₁₇H₁₅BrO₄
• 分子量: 363.20

F-17靶点实验

查看更多实验

实验名称：Antibiofilm activity against Pseudomonas aeruginosa PAO1 assessed as inhibition of bi... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL5512866

实验名称：Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3874919

实验名称：Antiproliferative activity against human ECA109 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3874920

实验名称：Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3874921

实验名称：Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3874922

实验名称：Binding affinity to human GRP78 at 1 uM measured after 30 mins by UF-ASMS analysis re... 来源：ChEMBL 靶标：Endoplasmic reticulum chaperone BiP External Id：CHEMBL4686292

实验名称：Antiangiogenic activity against VEGF-stimulated HUVEC assessed as reduction in cell v... 来源：ChEMBL 靶标：HUVEC External Id：CHEMBL4686295

实验名称：Antiangiogenic activity against VEGF-stimulated HUVEC assessed as reduction in cell v... 来源：ChEMBL 靶标：HUVEC External Id：CHEMBL4686294

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