Pomolic acid 3-acetate

• 常用名: Pomolic acid 3-acetate
• 英文名: Pomolic acid 3-acetate
• CAS号: 15914-62-2
• 分子量: 514.74
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₂H₅₀O₅
• 熔点: N/A
• 闪点: N/A

Pomolic acid 3-acetate用途

3-乙酸波莫酸是一种抗结核药,对结核分枝杆菌H37Rv的MIC为32μM[1]。

Pomolic acid 3-acetate名称

• 英文名: Pomolic acid 3-acetate

Pomolic acid 3-acetate生物活性

• 描述: 3-乙酸波莫酸是一种抗结核药,对结核分枝杆菌H37Rv的MIC为32μM[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 靶点实验:

  MIC: 32 μM (Mycobacterium tuberculosis H37Rv)[1]

• 体外研究: 3-乙酸波莫酸抑制 JB6型细胞转化,国际50为 8.1μg/mL[2]
• 参考文献:

  [1]. Wächter GA, et al. Antitubercular activity of pentacyclic triterpenoids from plants of Argentina and Chile. Phytomedicine. 1999 Nov;6(5):341-5.

  [2]. Carcache-Blanco EJ, et al. Potential cancer chemopreventive agents from Arbutus unedo. Nat Prod Res. 2006 Apr;20(4):327-34.

Pomolic acid 3-acetate物理化学性质

• 分子式: C₃₂H₅₀O₅
• 分子量: 514.74

Pomolic acid 3-acetate靶点实验

查看更多实验

实验名称：Inhibition of calf thymus Top1 assessed as reduction in supercoiled pBR322 DNA relaxa... 来源：ChEMBL 靶标：DNA topoisomerase I External Id：CHEMBL4623530

实验名称：Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 7... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4623532

实验名称：Inhibition of TDP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using 5'... 来源：ChEMBL 靶标：Tyrosyl-DNA phosphodiesterase 1 External Id：CHEMBL4623531

实验名称：Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL4623534

实验名称：Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by M... 来源：ChEMBL 靶标：A549 External Id：CHEMBL4623533

实验名称：Inhibition of TDP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) at 100 u... 来源：ChEMBL 靶标：Tyrosyl-DNA phosphodiesterase 1 External Id：CHEMBL4623537

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