K-Ras G12C-IN-1

• 常用名: K-Ras G12C-IN-1
• 英文名: K-Ras G12C-IN-1
• CAS号: 1629265-17-3
• 分子量: 448.342
• 密度: 1.3±0.1 g/cm3
• 沸点: 676.3±55.0 °C at 760 mmHg
• 分子式: C₂₂H₂₃Cl₂N₃O₃
• 熔点: N/A
• 闪点: 362.8±31.5 °C

K-Ras G12C-IN-1用途

K-Ras G12C-IN-1是突变型K-Ras G12C不可逆小分子抑制剂。

K-Ras G12C-IN-1名称

• 中文名: K-Ras G12C-IN-1
• 英文名: K-Ras G12C-IN-1

K-Ras G12C-IN-1生物活性

• 描述: K-Ras G12C-IN-1是突变型K-Ras G12C不可逆小分子抑制剂。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 拉斯
  研究领域 >> 癌症

K-Ras G12C-IN-1物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 676.3±55.0 °C at 760 mmHg
• 分子式: C₂₂H₂₃Cl₂N₃O₃
• 分子量: 448.342
• 闪点: 362.8±31.5 °C
• 精确质量: 447.111633
• LogP: 3.22
• InChIKey: ZJWLFLPGQCYBSE-UHFFFAOYSA-N
• SMILES: C=CC(=O)N1CCN(C(=O)CNc2cc(-c3ccccc3Cl)c(Cl)cc2OC)CC1
• 蒸汽压: 0.0±2.1 mmHg at 25°C
• 折射率: 1.615
• 储存条件: 2-8℃

K-Ras G12C-IN-1靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ... 来源：NCGC External Id：s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

实验名称：NCATS Human Liver Microsomal (HLM) Stability Profiling 来源：NCGC 靶标：N/A External Id：ADME-HLM1

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K-Ras G12C-IN-1英文别名

• 1-(4-{[(2',6-Dichloro-4-methoxy-3-biphenylyl)amino]acetyl}-1-piperazinyl)-2-propen-1-one