K-Ras G12C-IN-3

• 常用名: K-Ras G12C-IN-3
• 英文名: K-Ras G12C-IN-3
• CAS号: 1629268-19-4
• 分子量: 453.746
• 密度: 1.4±0.1 g/cm3
• 沸点: 655.0±55.0 °C at 760 mmHg
• 分子式: C₂₁H₁₉Cl₃N₂O₃
• 熔点: N/A
• 闪点: 349.9±31.5 °C

K-Ras G12C-IN-3用途

K-Ras G12C-IN-3是突变型K-Ras G12C不可逆小分子抑制剂。

K-Ras G12C-IN-3名称

• 中文名: K-Ras G12C-IN-3
• 英文名: K-Ras G12C-IN-3

K-Ras G12C-IN-3生物活性

• 描述: K-Ras G12C-IN-3是突变型K-Ras G12C不可逆小分子抑制剂。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 拉斯
  研究领域 >> 癌症

K-Ras G12C-IN-3物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 655.0±55.0 °C at 760 mmHg
• 分子式: C₂₁H₁₉Cl₃N₂O₃
• 分子量: 453.746
• 闪点: 349.9±31.5 °C
• 精确质量: 452.046112
• LogP: 3.39
• InChIKey: RPBHAPLCWWQJAK-UHFFFAOYSA-N
• SMILES: C=CC(=O)N1CCN(C(=O)c2cc(-c3cc(Cl)ccc3Cl)c(Cl)cc2OC)CC1
• 蒸汽压: 0.0±2.0 mmHg at 25°C
• 折射率: 1.604
• 储存条件: 2-8℃

K-Ras G12C-IN-3靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Confirmatory Screen for Target Class Profiling of Small Molecule Inhibitors of Methyl... 来源：NCGC External Id：MTASE-f-cherrypicks

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ... 来源：NCGC External Id：s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

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K-Ras G12C-IN-3英文别名

• 1-{4-[(2',5',6-Trichloro-4-methoxy-3-biphenylyl)carbonyl]-1-piperazinyl}-2-propen-1-one