Cipepofol

• 常用名: Cipepofol
• 英文名: Cipepofol
• CAS号: 1637741-58-2
• 分子量: 204.31
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₄H₂₀O
• 熔点: N/A
• 闪点: N/A

Cipepofol用途

Cipepofol(HSK3486)是一种镇静催眠剂,是一种γ-氨基丁酸(GABA)受体增强剂[1]。

Cipepofol名称

• 英文名: Cipepofol

Cipepofol生物活性

• 描述: Cipepofol(HSK3486)是一种镇静催眠剂,是一种γ-氨基丁酸(GABA)受体增强剂[1]。
• 相关类别:
  信号通路 >> 跨膜转运 >> GABA受体
  研究领域 >> 神经疾病
  信号通路 >> 神经信号通路 >> GABA受体
• 参考文献:

  [1]. Li X, et al. Safety, Pharmacokinetics, and Pharmacodynamics of a Single Bolus of the γ-aminobutyric Acid (GABA) Receptor Potentiator HSK3486 in Healthy Chinese Elderly and Non-elderly. Front Pharmacol. 2021;12:735700. Published 2021 Aug 27.

Cipepofol物理化学性质

• 分子式: C₁₄H₂₀O
• 分子量: 204.31
• InChIKey: BMEARIQHWSVDBS-SNVBAGLBSA-N
• SMILES: CC(C)c1cccc(C(C)C2CC2)c1O

Cipepofol靶点实验

查看更多实验

实验名称：Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4043677

实验名称：Clearance in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4043678

实验名称：AUC (0 to t) in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4043675

实验名称：Half life in Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4043676

实验名称：Displacement of [35S]TBPS from GABAA receptor in Wistar rat cerebral cortex membranes... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4043673

实验名称：Displacement of [35S]TBPS from GABAA receptor in Wistar rat cerebral cortex membranes... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4043674

实验名称：Displacement of [35S]TBPS from GABAA receptor in Wistar rat cerebral cortex membranes... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4043672

实验名称：Toxicity in iv dosed ICR mouse administered 7 to 8 doses at 10 secs for each dose 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4043685

实验名称：Anesthetic activity in iv dosed ICR mouse assessed as dose required to produce 10 min... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4043686

实验名称：Half life in Beagle dog at 2 mg/kg, iv administered as single bolus dose by LC-MS/MS ... 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL4020400

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