地拉考昔

• 常用名: 地拉考昔
• 英文名: deracoxib
• CAS号: 169590-41-4
• 分子量: 397.372
• 密度: 1.5±0.1 g/cm3
• 沸点: 575.5±60.0 °C at 760 mmHg
• 分子式: C₁₇H₁₄F₃N₃O₃S
• 熔点: N/A
• 闪点: 301.9±32.9 °C

地拉考昔用途

Deracoxib是COX-2选择性抑制剂,是非麻醉性,非甾体抗炎化合物。

地拉考昔名称

• 中文名: 地拉考昔
• 英文名: deracoxib
• 中文别名: 4-(3-(二氟甲基)-5-(3-氟-4-甲氧基苯基)-1H-吡唑-1-基)苯磺酰胺

地拉考昔生物活性

• 描述: Deracoxib是COX-2选择性抑制剂,是非麻醉性,非甾体抗炎化合物。
• 相关类别:
  研究领域 >> 炎症/免疫
• 靶点实验:

  COX-2

• 参考文献:

  [1]. Royals, S.R., et al., Investigation of the effects of deracoxib and piroxicam on the in vitro viability of osteosarcoma cells from dogs. Am J Vet Res, 2005. 66(11): p. 1961-7.

  [2]. Ustun Alkan, F., et al., The effects of piroxicam and deracoxib on canine mammary tumour cell line. ScientificWorldJournal, 2012. 2012: p. 976740.

  [3]. Bienhoff, S.E., et al., Efficacy and safety of deracoxib for control of postoperative pain and inflammation associated with soft tissue surgery in dogs. Vet Surg, 2012. 41(3): p. 336-44.

  [4]. McMillan, S.K., et al., Antitumor effects of deracoxib treatment in 26 dogs with transitional cell carcinoma of the urinary bladder. J Am Vet Med Assoc, 2011. 239(8): p. 1084-9.

地拉考昔物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 575.5±60.0 °C at 760 mmHg
• 分子式: C₁₇H₁₄F₃N₃O₃S
• 分子量: 397.372
• 闪点: 301.9±32.9 °C
• 精确质量: 397.070801
• PSA: 95.59000
• LogP: 2.54
• InChIKey: WAZQAZKAZLXFMK-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2cc(C(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1F
• 外观性状: 粉末
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.610
• 储存条件: -20℃

地拉考昔安全信息

• 海关编码: 2935009090

地拉考昔海关

• 海关编码: 2935009090
• 中文概述: 2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

地拉考昔靶点实验

查看更多实验

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：Increase the activity of the Burkholderia fixLJ 2-component system 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Burkholderia multivorans External Id：HMS1625

实验名称：In vitro inhibitory activity against canine prostaglandin G/H synthase 2. 来源：ChEMBL 靶标：Prostaglandin G/H synthase 2 External Id：CHEMBL760077

实验名称：p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree... 来源：824 靶标：N/A External Id：P53600

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce... 来源：824 靶标：N/A External Id：P53MS958

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary 来源：824 External Id：P53MS482

实验名称：p53 small molecule agonists, cell-based qHTS assay 来源：824 External Id：P53344

实验名称：p53 small molecule agonists, cell-based qHTS assay with human liver microsomes 来源：824 靶标：tumor suppressor p53 [Homo sapiens] External Id：P53MS233

实验名称：p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ... 来源：824 靶标：N/A External Id：P53MS837

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地拉考昔英文别名

• deracoxib
• 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)pyrazol-1-yl]benzenesulfonamide
• 4-(3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl)benzenesulfonamide
• 4-[3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzenesulfonamide