O4I1

• 常用名: O4I1
• 英文名: O4I1
• CAS号: 175135-47-4
• 分子量: 253.296
• 密度: 1.1±0.1 g/cm3
• 沸点: 424.5±30.0 °C at 760 mmHg
• 分子式: C₁₆H₁₅NO₂
• 熔点: 140ºC
• 闪点: 154.8±17.8 °C

O4I1用途

O4I1是一种有效的Oct3/4诱导剂。

O4I1名称

• 中文名: 2-(4-[(4-甲氧基苄基)氧基]苯基)乙腈
• 英文名: 2-[4-[(4-methoxyphenyl)methoxy]phenyl]acetonitrile

O4I1生物活性

• 描述: O4I1是一种有效的Oct3/4诱导剂。
• 相关类别:
  信号通路 >> 干细胞及 Wnt 通路 >> OCT3/4
  研究领域 >> 其他
• 参考文献:

  [1]. Cheng X, et al. Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and Derivatives as Potent Oct3/4 Inducers. J Med Chem. 2015 Jun 25;58(12):4976-4983.

  [2]. Mrowka, et al. Method for activating OCT4 for induction of pluripotent stem cell formation. From PCT Int. Appl. (2014), WO 2014000814 A1 20140103.

O4I1物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 424.5±30.0 °C at 760 mmHg
• 熔点: 140ºC
• 分子式: C₁₆H₁₅NO₂
• 分子量: 253.296
• 闪点: 154.8±17.8 °C
• 精确质量: 253.110275
• PSA: 42.25000
• LogP: 2.93
• InChIKey: QJEJLARVLKHYFW-UHFFFAOYSA-N
• SMILES: COc1ccc(COc2ccc(CC#N)cc2)cc1
• 外观性状: light yellow solid
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.570
• 储存条件: -20℃

O4I1MSDS

O4I1MSDS英文版

O4I1安全信息

• 危害码 (欧洲): Xn:Harmful;
• 风险声明 (欧洲): R20/21/22
• 安全声明 (欧洲): S36/37
• 海关编码: 2926909090

O4I1海关

• 海关编码: 2926909090
• 中文概述: 2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

O4I1靶点实验

查看更多实验

实验名称：Activation of human Oct3/4 in HEK293 cells transfected with firefly luciferase gene a... 来源：ChEMBL 靶标：POU domain, class 5, transcription factor 1 External Id：CHEMBL3583936

实验名称：Activation of human Oct3/4 in HEK293 cells transfected with firefly luciferase gene a... 来源：ChEMBL 靶标：POU domain, class 5, transcription factor 1 External Id：CHEMBL3583937

实验名称：Activation of human Oct3/4 in HEK293 cells transfected with firefly luciferase gene a... 来源：ChEMBL 靶标：POU domain, class 5, transcription factor 1 External Id：CHEMBL3583934

实验名称：Activation of human Oct3/4 in HEK293 cells transfected with firefly luciferase gene a... 来源：ChEMBL 靶标：POU domain, class 5, transcription factor 1 External Id：CHEMBL3583935

实验名称：Induction of human Oct3/4 expression in HEK293 cells transfected with firefly lucifer... 来源：ChEMBL 靶标：HEK293 External Id：CHEMBL3583940

实验名称：Activation of human Oct3/4 in NCCIT cells transfected with firefly luciferase gene as... 来源：ChEMBL 靶标：POU domain, class 5, transcription factor 1 External Id：CHEMBL3583941

实验名称：Activation of human Oct3/4 in HEK293 cells transfected with firefly luciferase gene a... 来源：ChEMBL 靶标：POU domain, class 5, transcription factor 1 External Id：CHEMBL3583938

实验名称：Induction of human Oct3/4 expression in HEK293 cells transfected with firefly lucifer... 来源：ChEMBL 靶标：HEK293 External Id：CHEMBL3583939

实验名称：Induction of human Sox2 protein expression in HEK293 cells assessed as increase in pr... 来源：ChEMBL 靶标：HEK293 External Id：CHEMBL3584472

实验名称：Induction of human Nanog protein expression in HEK293 cells assessed as increase in p... 来源：ChEMBL 靶标：HEK293 External Id：CHEMBL3584473

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O4I1英文别名

• 2-[4-[(4-Methoxyphenyl)methoxy]phenyl]-acetonitrile
• 4-(4-methoxybenzyloxy)benzylnitrile
• {4-[(4-Methoxybenzyl)oxy]phenyl}acetonitrile
• O4I1
• 2-(4-((4-Methoxybenzyl)oxy)phenyl)acetonitrile
• 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE
• O4I-1