(RS)-3,4-DCPG

• 常用名: (RS)-3,4-DCPG
• 英文名: (RS)-3,4-DCPG
• CAS号: 176796-64-8
• 分子量: 239.18
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₀H₉NO₆
• 熔点: N/A
• 闪点: N/A

(RS)-3,4-DCPG用途

(R,S)-3,4-Dicarboxyphenylglycine ((RS)-3,4-DCPG) 是一种 AMPA 受体拮抗剂。(R,S)-3,4-Dicarboxyphenylglycine 能拮抗 AMPA 介导的新生大鼠运动神经元去极化作用。(R,S)-3,4-Dicarboxyphenylglycine 可用于神经系统疾病的研究。

(RS)-3,4-DCPG名称

• 英文名: 4-[amino(carboxy)methyl]phthalic acid

(RS)-3,4-DCPG生物活性

• 描述: (R,S)-3,4-Dicarboxyphenylglycine ((RS)-3,4-DCPG) 是一种 AMPA 受体拮抗剂。(R,S)-3,4-Dicarboxyphenylglycine 能拮抗 AMPA 介导的新生大鼠运动神经元去极化作用。(R,S)-3,4-Dicarboxyphenylglycine 可用于神经系统疾病的研究。
• 相关类别:
  信号通路 >> 神经信号通路 >> iGluR
  研究领域 >> 神经疾病
  信号通路 >> 跨膜转运 >> iGluR
• 靶点实验:

  AMPA[1].

• 参考文献:

  [1]. Thomas NK, et al. Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones. Eur J Pharmacol. 1997 Nov 5;338(2):111-6.

(RS)-3,4-DCPG物理化学性质

• 分子式: C₁₀H₉NO₆
• 分子量: 239.18
• 精确质量: 239.04300
• PSA: 137.92000
• LogP: 0.86770
• InChIKey: IJVMOGKBEVRBPP-UHFFFAOYSA-N
• SMILES: NC(C(=O)O)c1ccc(C(=O)O)c(C(=O)O)c1

(RS)-3,4-DCPG靶点实验

查看更多实验

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808149

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Enzymatic assay of human HDAC6 with custom peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808150

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Tocris HTS for Inhibitors of Aerobactin Synthetase lucA 来源：23265 External Id：IucA Pilot Assay Tocris Library

共8条，当前第1页，共1页

1

(RS)-3,4-DCPG英文别名

• pacap 1-27
• hms3267f06