FR182024

• 常用名: FR182024
• 英文名: FR182024
• CAS号: 179034-83-4
• 分子量: 448.54
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₆N₄O₄S₃
• 熔点: N/A
• 闪点: N/A

FR182024用途

FR182024是一种具有强效抗幽门螺杆菌活性的头孢烯衍生物[1]。

FR182024名称

• 英文名: (6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

FR182024生物活性

• 描述: FR182024是一种具有强效抗幽门螺杆菌活性的头孢烯衍生物[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Yoshida Y, et al. Synthesis and anti-Helicobacter pylori activity of FR182024, a new cephem derivative. Bioorg Med Chem Lett. 1999 Nov 1;9(21):3123-6.

FR182024物理化学性质

• 分子式: C₁₈H₁₆N₄O₄S₃
• 分子量: 448.54
• 精确质量: 448.03300
• PSA: 194.82000
• LogP: 2.65560
• InChIKey: IQURDYALUUXKIJ-CZUORRHYSA-N
• SMILES: Cc1nnc(SC2=C(C(=O)O)N3C(=O)C(NC(=O)Cc4ccccc4)C3SC2)s1

FR182024靶点实验

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实验名称：The compound was evaluated in vitro for the minimum inhibitory concentration against ... 来源：ChEMBL 靶标：Helicobacter pylori External Id：CHEMBL698557

实验名称：The compound was evaluated in vitro for the minimum inhibitory concentration against ... 来源：ChEMBL 靶标：Helicobacter pylori External Id：CHEMBL698556

实验名称：The compound was evaluated in vitro for the minimum inhibitory concentration against ... 来源：ChEMBL 靶标：Helicobacter pylori External Id：CHEMBL698559

实验名称：The compound was tested against Bacteroides fragilis FP784 and its stability towards ... 来源：ChEMBL 靶标：Beta-lactamase External Id：CHEMBL654131

实验名称：The compound was evaluated in vitro for the minimum inhibitory concentration against ... 来源：ChEMBL 靶标：Helicobacter pylori External Id：CHEMBL698558

实验名称：The compound was tested against Bacteroides fragilis FP784 and its stability towards ... 来源：ChEMBL 靶标：Beta-lactamase External Id：CHEMBL654133

实验名称：The compound was evaluated in vivo for the therapeutic efficacy at 0.1 mg/kg in mouse... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL744255

实验名称：The compound was tested against Bacteroides fragilis FP784 its stability towards beta... 来源：ChEMBL 靶标：Beta-lactamase External Id：CHEMBL654134

实验名称：The compound was evaluated in vivo for the therapeutic efficacy at 0.32 mg/kg in mous... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL744258

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FR182024英文别名

• unii-9031sv3fwe