1,2,3,4-四羟基去甲哈尔满-1-酮

• 常用名: 1,2,3,4-四羟基去甲哈尔满-1-酮
• 英文名: 1H-Pyrido[3,4-b]indol-1-one,2,3,4,9-tetrahydro
• CAS号: 17952-82-8
• 分子量: 186.21000
• 密度: 1.318g/cm3
• 沸点: 529.2ºC at 760mmHg
• 分子式: C₁₁H₁₀N₂O
• 熔点: N/A
• 闪点: 273.9ºC

1,2,3,4-四羟基去甲哈尔满-1-酮用途

1,2,3,4-四氢去氢骆驼蓬-1-酮是一种从印度尼西亚海绵中提取的具有抗传染病和热带寄生虫病活性的曼扎明生物碱[1]。

1,2,3,4-四羟基去甲哈尔满-1-酮名称

• 中文名: 1,2,3,4-四羟基去甲哈尔满-1-酮
• 英文名: 2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one

1,2,3,4-四羟基去甲哈尔满-1-酮生物活性

• 描述: 1,2,3,4-四氢去氢骆驼蓬-1-酮是一种从印度尼西亚海绵中提取的具有抗传染病和热带寄生虫病活性的曼扎明生物碱[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Karumanchi V Rao, et al. New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge. J Nat Prod. 2003 Jun;66(6):823-8.

1,2,3,4-四羟基去甲哈尔满-1-酮物理化学性质

• 密度: 1.318g/cm3
• 沸点: 529.2ºC at 760mmHg
• 分子式: C₁₁H₁₀N₂O
• 分子量: 186.21000
• 闪点: 273.9ºC
• 精确质量: 186.07900
• PSA: 44.89000
• LogP: 1.78260
• InChIKey: FZHZQHNKCPJTNQ-UHFFFAOYSA-N
• SMILES: O=C1NCCc2c1[nH]c1ccccc21
• 蒸汽压: 2.75E-11mmHg at 25°C
• 折射率: 1.693
• 储存条件: 2-8℃

1,2,3,4-四羟基去甲哈尔满-1-酮靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL4296186

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Identifying Sarm1 TIR NADase inhibitors through high throughput HPLC assay 来源：24386 靶标：N/A External Id：Sarm1 TIR NADase inhibitors

实验名称：Cytotoxicity against human HCT-116 cells incubated for 48 hrs by neutral red dye base... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL5242187

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1,2,3,4-四羟基去甲哈尔满-1-酮英文别名

• 2,3,4-trihydrobeta-carbolin-1-one
• L-Oxonoreleagnine
• 2,3,4,9-tetrahydro-1h-b-carbolin-1-one