茚地那韦

更新时间：2026-07-04 12:55:53

茚地那韦结构式	常用名	茚地那韦	英文名	INDINAVIR (100 MG)F0D3080.971MG/MG(AI)
	CAS号	180683-37-8	分子量	631.80500
	密度	N/A	沸点	877.9ºC at 760 mmHg
	分子式	C₃₆H₄₉N₅O₅	熔点	158 °C
	MSDS	N/A	闪点	484.7ºC
	符号	GHS07	信号词	Warning

中文名	茚地那韦
英文名	Indinavir monohydrate
英文别名	更多

沸点	877.9ºC at 760 mmHg
熔点	158 °C
分子式	C₃₆H₄₉N₅O₅
分子量	631.80500
闪点	484.7ºC
精确质量	631.37300
PSA	134.24000
LogP	4.35900
InChIKey	XTYSXGHMTNTKFH-BDEHJDMKSA-N
SMILES	CC(C)(C)NC(=O)C1CN(Cc2cccnc2)CCN1CC(O)CC(Cc1ccccc1)C(=O)NC1c2ccccc2CC1O.O
外观性状	白色结晶粉末
蒸汽压	5.56E-33mmHg at 25°C
储存条件	室温

符号	GHS07
信号词	Warning
危害声明	H315
危害码 (欧洲)	Xi
危险品运输编码	NONH for all modes of transport

Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs.

Biomaterials 37 , 383-94, (2015)

With the advent of the Highly Active Antiretroviral Therapy, the morbidity and the mortality associated to HIV have been considerably reduced. However, 35-40 million people bear the infection worldwid...

Blood-brain barrier pharmacoproteomics-based reconstruction of the in vivo brain distribution of P-glycoprotein substrates in cynomolgus monkeys.

J. Pharmacol. Exp. Ther. 350(3) , 578-88, (2014)

The aim of this study was to investigate whether in vivo drug distribution in brain in monkeys can be reconstructed by integrating four factors: protein expression levels of P-glycoprotein (P-gp)/mult...

Drug susceptibility to etravirine and darunavir among Human Immunodeficiency Virus Type 1-derived pseudoviruses in treatment-experienced patients with HIV/AIDS in South Korea.

Virol. J. 12(1) , 53, (2015)

In South Korea, about 20 types of antiretroviral drugs are used in the treatment of patients with human immunodeficiency virus/acquired immune deficiency syndrome. Since 2010, raltegravir, etravirine,...

(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide,hydrate