茚地那韦

茚地那韦名称

[ CAS 号 ]:
180683-37-8

[ 中文名 ]:
茚地那韦

[ 英文名 ]:
INDINAVIR (100 MG)F0D3080.971MG/MG(AI)

[英文别名 ]:

茚地那韦物理化学性质

[ 沸点 ]:
877.9ºC at 760 mmHg

[ 熔点 ]:
158 °C

[ 分子式 ]:
C36H49N5O5

[ 分子量 ]:
631.80500

[ 闪点 ]:
484.7ºC

[ 精确质量 ]:
631.37300

[ PSA ]:
134.24000

[ LogP ]:
4.35900

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
5.56E-33mmHg at 25°C

[ 储存条件 ]:
室温

茚地那韦安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

茚地那韦文献

Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs.

Biomaterials 37 , 383-94, (2015)

With the advent of the Highly Active Antiretroviral Therapy, the morbidity and the mortality associated to HIV have been considerably reduced. However, 35-40 million people bear the infection worldwid...

Blood-brain barrier pharmacoproteomics-based reconstruction of the in vivo brain distribution of P-glycoprotein substrates in cynomolgus monkeys.

J. Pharmacol. Exp. Ther. 350(3) , 578-88, (2014)

The aim of this study was to investigate whether in vivo drug distribution in brain in monkeys can be reconstructed by integrating four factors: protein expression levels of P-glycoprotein (P-gp)/mult...

Drug susceptibility to etravirine and darunavir among Human Immunodeficiency Virus Type 1-derived pseudoviruses in treatment-experienced patients with HIV/AIDS in South Korea.

Virol. J. 12(1) , 53, (2015)

In South Korea, about 20 types of antiretroviral drugs are used in the treatment of patients with human immunodeficiency virus/acquired immune deficiency syndrome. Since 2010, raltegravir, etravirine,...


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