2-(4-(4-氟苯氧基)亚苄基)肼甲酰胺

• 常用名: 2-(4-(4-氟苯氧基)亚苄基)肼甲酰胺
• 英文名: Co 102862
• CAS号: 181144-66-1
• 分子量: 273.26
• 密度: 1.278g/cm3
• 沸点: N/A
• 分子式: C₁₄H₁₂FN₃O₂
• 熔点: N/A
• 闪点: N/A

2-(4-(4-氟苯氧基)亚苄基)肼甲酰胺用途

Co 102862(V 102862)是一种有效的、广谱的、依赖于状态的钠离子通道阻滞剂。Co 102862也是一种口服活性抗惊厥药[1]。

2-(4-(4-氟苯氧基)亚苄基)肼甲酰胺名称

• 中文名: 2-(4-(4-氟苯氧基)亚苄基)肼甲酰胺
• 英文名: Co 102862,2-[[4-(4-Fluorophenoxy)phenyl]methylene]hydrazinecarboxamide

2-(4-(4-氟苯氧基)亚苄基)肼甲酰胺生物活性

• 描述: Co 102862(V 102862)是一种有效的、广谱的、依赖于状态的钠离子通道阻滞剂。Co 102862也是一种口服活性抗惊厥药[1]。
• 相关类别:
  信号通路 >> 跨膜转运 >> 钠通道
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Ilyin VI, et al. V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of mammalian voltage-gated sodium channels. Br J Pharmacol. 2005 Mar;144(6):801-12.

2-(4-(4-氟苯氧基)亚苄基)肼甲酰胺物理化学性质

• 密度: 1.278g/cm3
• 分子式: C₁₄H₁₂FN₃O₂
• 分子量: 273.26
• 精确质量: 273.09100
• PSA: 76.71000
• LogP: 3.71140
• InChIKey: MHUUDVZSPFRUSK-RQZCQDPDSA-N
• SMILES: NC(=O)NN=Cc1ccc(Oc2ccc(F)cc2)cc1
• 折射率: 1.589
• 储存条件: 2-8°C， 干燥

2-(4-(4-氟苯氧基)亚苄基)肼甲酰胺安全信息

• 海关编码: 2928000090

2-(4-(4-氟苯氧基)亚苄基)肼甲酰胺海关

• 海关编码: 2928000090
• 中文概述: 2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

2-(4-(4-氟苯氧基)亚苄基)肼甲酰胺靶点实验

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实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Compound was tested for anticonvulsant activity after Oral Administration into Rats b... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL773187

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Tocris HTS for Inhibitors of Aerobactin Synthetase lucA 来源：23265 External Id：IucA Pilot Assay Tocris Library

实验名称：Protection index = TD50/ED50 (MES) 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL842058

实验名称：Dissociation constant for binding to resting state of rat brain NaIIa (rNav1.2) -B2 c... 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL835114

实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808149

实验名称：EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Rea... 来源：Broad Institute 靶标：histone-lysine N-methyltransferase EZH2 isoform a [Homo sapiens] External Id：2125-01_Inhibitor_SinglePoint_HTS_Activity

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2-(4-(4-氟苯氧基)亚苄基)肼甲酰胺英文别名

• MFCD00953614