MSP3

• 常用名: MSP3
• 英文名: MSP3
• CAS号: 1820968-63-5
• 分子量: 305.392
• 密度: 1.2±0.1 g/cm3
• 沸点: 552.3±50.0 °C at 760 mmHg
• 分子式: C₁₆H₁₉NO₃S
• 熔点: N/A
• 闪点: 287.8±30.1 °C

MSP3用途

MSP-3是一种有效的TRPV1激动剂,EC50为0.87μM。MSP-3具有神经保护和抗伤害作用[1]。

MSP3名称

• 英文名: MSP-3

MSP3生物活性

• 描述: MSP-3是一种有效的TRPV1激动剂,EC50为0.87μM。MSP-3具有神经保护和抗伤害作用[1]。
• 相关类别:
  信号通路 >> 跨膜转运 >> TRP频道
  研究领域 >> 神经疾病
• 靶点实验:

  TRPV1:0.87 μM (EC50)

• 参考文献:

  [1]. Aiello F, et, al. Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress. ACS Chem Neurosci. 2016 Jun 15;7(6):737-48.

MSP3物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 552.3±50.0 °C at 760 mmHg
• 分子式: C₁₆H₁₉NO₃S
• 分子量: 305.392
• 闪点: 287.8±30.1 °C
• 精确质量: 305.108551
• LogP: 2.01
• InChIKey: HCUVEUVIUAJXRB-UHFFFAOYSA-N
• SMILES: COc1cc(CNC(=O)CCCc2cccs2)ccc1O
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.592

MSP3靶点实验

查看更多实验

实验名称：Agonist activity at human recombinant TRPV1 expressed in HEK293 cells assessed as inc... 来源：ChEMBL 靶标：Transient receptor potential cation channel subfamily V member 1 External Id：CHEMBL5342625

实验名称：Antagonist activity at human recombinant TRPV1 expressed in HEK293 cells assessed as ... 来源：ChEMBL 靶标：Transient receptor potential cation channel subfamily V member 1 External Id：CHEMBL5342621

实验名称：Agonist activity at human recombinant TRPV1 expressed in HEK293 cells assessed as inc... 来源：ChEMBL 靶标：Transient receptor potential cation channel subfamily V member 1 External Id：CHEMBL5342620

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MSP3英文别名

• MSP-3
• N-(4-Hydroxy-3-methoxybenzyl)-4-(2-thienyl)butanamide
• N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide