SARS-CoV-2-IN-18

• 常用名: SARS-CoV-2-IN-18
• 英文名: SARS-CoV-2-IN-18
• CAS号: 184904-82-3
• 分子量: 330.34
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₄N₂O₃
• 熔点: N/A
• 闪点: N/A

SARS-CoV-2-IN-18用途

SARS-CoV-2-IN-18(化合物26)是一种有效的SARS-CoV-2 3C样蛋白酶抑制剂,IC50为45 nM【1】。

SARS-CoV-2-IN-18名称

• 英文名: SARS-CoV-2-IN-18

SARS-CoV-2-IN-18生物活性

• 描述: SARS-CoV-2-IN-18(化合物26)是一种有效的SARS-CoV-2 3C样蛋白酶抑制剂,IC50为45 nM【1】。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> SARS冠状病毒
• 靶点实验:

  IC50: 45 nM (SARS-CoV-2 3C-like protease)[1]

• 参考文献:

  [1]. Pei Liu, et al. Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds. Eur J Med Chem. 2020 Nov 15;206:112702.

SARS-CoV-2-IN-18物理化学性质

• 分子式: C₂₀H₁₄N₂O₃
• 分子量: 330.34
• InChIKey: NTNYHMJYSGPGCQ-UHFFFAOYSA-N
• SMILES: NC(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc2ccccc2c1

SARS-CoV-2-IN-18靶点实验

查看更多实验

实验名称：Compound was tested for the 50% toxic concentration against Human Rhinovirus-14 (HRV-... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL691125

实验名称：Compound was tested for the antiviral activity against Human Rhinovirus -14(HRV-14) i... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL697148

实验名称：Inhibition of SARS-CoV-2 MPro at 5 uM using MCAAVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL5330099

实验名称：Cytotoxicity against African green monkey Vero E6 assessed as inhibition of cell grow... 来源：ChEMBL 靶标：Vero C1008 External Id：CHEMBL5330097

实验名称：No assay is provided from Article 10.1002/med.21724: "The recent outbreaks of human c... 来源：BindingDB 靶标：N/A External Id：BindingDB_8918_1

实验名称：Inhibition of SARS-CoV-2 MPro at 5 uM using MCAAVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL5330098

实验名称：Inhibition of SARS-CoV-2 MPro using MCAAVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubat... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL5330095

实验名称：Inhibition of SARS CoV 3C-like protease 来源：ChEMBL 靶标：Replicase polyprotein 1a External Id：CHEMBL868157

实验名称：Cytotoxicity against African green monkey Vero E6 assessed as inhibition of cell grow... 来源：ChEMBL 靶标：Vero C1008 External Id：CHEMBL5330096

实验名称：Inhibition of SARS CoV2 C-terminal His6-tagged 3CL protease expressed in Escherichia ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4773797

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