Pandinotoxin Kα

更新时间：2025-08-26 17:24:15

Pandinotoxin Kα结构式	常用名	Pandinotoxin Kα	英文名	Pandinotoxin Kα
	CAS号	185529-64-0	分子量	4033.71
	密度	N/A	沸点	N/A
	分子式	C₁₆₉H₂₆₇N₅₃O₄₈S₇	熔点	N/A
	MSDS	美版	闪点	N/A

Pandinotoxin Kα用途

Pandininotoxin Kα 是从帝蝎 Pandinus imperator 的毒液中分离出来的,是 A 型钾通道 (potassium channel) 的抑制剂。

英文名	PANDINOTOXIN-K ALPHA

描述	Pandininotoxin Kα 是从帝蝎 Pandinus imperator 的毒液中分离出来的,是 A 型钾通道 (potassium channel) 的抑制剂。
相关类别	研究领域 >> 癌症信号通路 >> 跨膜转运 >> 钾通道
靶点实验	Kv4.3 Kv3.4 Kv1.4
参考文献	[1]. T C Tenenholz, et al. Solution Structure for Pandinus Toxin K-α (PiTX-Kα), a Selective Blocker of A-Type Potassium Channels. Biochemistry. 1997 Mar 11;36(10):2763-71. [2]. Targeting Kai-Zheng Duan, et al. A-type K(+) channels in primary sensory neurons for bone cancer pain in a rat model. Pain.2012 Mar;153(3):562-574.

分子式	C₁₆₉H₂₆₇N₅₃O₄₈S₇
分子量	4033.71
外观性状	powder
储存条件	−20°C

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码	NONH for all modes of transport
WGK德国	3

Three new toxins from the scorpion Pandinus imperator selectively block certain voltage-gated K+ channels.

Mol. Pharmacol. 50 , 1167-1177, (1996)

Three 35-amino acid peptide K+ channel toxins (pandinotoxins) were purified from the venom of the scorpion Pandinus imperaton the toxins are designated pandinotoxin (PiTX)-K alpha, PiTX-K beta, and Pi...

Scorpion toxin block of the early K+ current (IKf) in rat dorsal root ganglion neurones.

J. Physiol. 503 2 , 285-301, (1997)

1. The ability of three structurally homologous scorpion toxins to block voltage-dependent K+ currents in rat dorsal root ganglion neurones was examined using the patch-clamp technique. 2. Neurones wi...

Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels.

Biochemistry 36 , 2763-2771, (1997)

PiTX-K alpha, a 35-residue peptide recently isolated from the venom of Pandinus imperator, blocks the rapidly inactivating (A-type) K+ channel(s) in rat brain synaptosomes and the cloned Kv 1.2 potass...

本网页内容来自不同专业数据源，如对内容有疑义，欢迎联系service1@chemsrc.com。

我想出现在这里：

Pandinotoxin Kα

Pandinotoxin Kα用途

Pandinotoxin Kα名称

Pandinotoxin Kα生物活性

Pandinotoxin Kα物理化学性质

Pandinotoxin Kα安全信息

Pandinotoxin Kα文献3

本网页内容来自不同专业数据源，如对内容有疑义，欢迎联系service1@chemsrc.com。