卢立康唑

更新时间：2025-08-20 18:18:02

卢立康唑结构式	常用名	卢立康唑	英文名	Luliconazole
	CAS号	187164-19-8	分子量	354.277
	密度	1.5±0.1 g/cm3	沸点	499.1±55.0 °C at 760 mmHg
	分子式	C₁₄H₉Cl₂N₃S₂	熔点	N/A
	MSDS	N/A	闪点	255.6±31.5 °C

卢立康唑用途

Luliconazole(NND 502)是抗真菌剂,可用于局部的脚癣治疗。

中文名	卢立康唑
英文名	(2E)-2-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-ylacetonitrile
中文别名	4-(2,4-二氯苯基)-1,3-二硫戊环-2-叉-1-咪唑基乙腈 \| 卢利康唑
英文别名	更多

描述	Luliconazole(NND 502)是抗真菌剂,可用于局部的脚癣治疗。
相关类别	信号通路 >> 抗感染 >> 真菌研究领域 >> 感染
参考文献	[1]. In vitro antifungal activities of luliconazole, a new topical imidazole By Koga, Hiroyasu; Nanjoh, Yasuko; Makimura, Koichi; Tsuboi, Ryoji From Medical Mycology (2009), 47(6), 640-647. [2]. Koga H, Nanjoh Y, Kaneda H, Yamaguchi H, Tsuboi R. Short-term therapy with luliconazole, a novel topical antifungal imidazole, in guinea pig models of tinea corporis and tinea pedis. Antimicrob Agents Chemother. 2012 Jun;56(6):3138-43. [3]. Ghannoum MA, Long L, Kim HG, Cirino AJ, Miller AR, Mallefet P. Efficacy of terbinafine compared to lanoconazole and luliconazole in the topical treatment of dermatophytosis in a guinea pig model. Med Mycol. 2010 May;48(3):491-7. [4]. Koga H, Nanjoh Y, Makimura K, Tsuboi R. In vitro antifungal activities of luliconazole, a new topical imidazole. Med Mycol. 2009;47(6):640-7. [5]. Tanaka T, Satoh T, Yokozeki H. Allergic contact dermatitis from luliconazole: implication of the dithioacetal structure. Acta Derm Venereol. 2007;87(3):271-2.

描述

Luliconazole(NND 502)是抗真菌剂,可用于局部的脚癣治疗。

相关类别

信号通路 >> 抗感染 >> 真菌

研究领域 >> 感染

参考文献

[1]. In vitro antifungal activities of luliconazole, a new topical imidazole By Koga, Hiroyasu; Nanjoh, Yasuko; Makimura, Koichi; Tsuboi, Ryoji From Medical Mycology (2009), 47(6), 640-647.

[2]. Koga H, Nanjoh Y, Kaneda H, Yamaguchi H, Tsuboi R. Short-term therapy with luliconazole, a novel topical antifungal imidazole, in guinea pig models of tinea corporis and tinea pedis. Antimicrob Agents Chemother. 2012 Jun;56(6):3138-43.

[3]. Ghannoum MA, Long L, Kim HG, Cirino AJ, Miller AR, Mallefet P. Efficacy of terbinafine compared to lanoconazole and luliconazole in the topical treatment of dermatophytosis in a guinea pig model. Med Mycol. 2010 May;48(3):491-7.

[4]. Koga H, Nanjoh Y, Makimura K, Tsuboi R. In vitro antifungal activities of luliconazole, a new topical imidazole. Med Mycol. 2009;47(6):640-7.

[5]. Tanaka T, Satoh T, Yokozeki H. Allergic contact dermatitis from luliconazole: implication of the dithioacetal structure. Acta Derm Venereol. 2007;87(3):271-2.

密度	1.5±0.1 g/cm3
沸点	499.1±55.0 °C at 760 mmHg
分子式	C₁₄H₉Cl₂N₃S₂
分子量	354.277
闪点	255.6±31.5 °C
精确质量	352.961487
PSA	92.21000
LogP	3.98
InChIKey	YTAOBBFIOAEMLL-REQDGWNSSA-N
SMILES	N#CC(=C1SCC(c2ccc(Cl)cc2Cl)S1)n1ccnc1
蒸汽压	0.0±1.3 mmHg at 25°C
折射率	1.734
储存条件	-20°C

危害码 (欧洲)	Xi

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
来源：NCGC
External Id：SNCA-p-activity-luciferase

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
来源：824
External Id：CYP273

实验名称：p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
来源：824
靶标：N/A
External Id：P53600

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
来源：824
靶标：N/A
External Id：P53MS958

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
来源：824
External Id：P53MS482

实验名称：p53 small molecule agonists, cell-based qHTS assay
来源：824
External Id：P53344

实验名称：p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
来源：824
靶标：tumor suppressor p53 [Homo sapiens]
External Id：P53MS233

实验名称：p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
来源：824
靶标：N/A
External Id：P53MS837

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
来源：824
靶标：tumor suppressor p53 [Homo sapiens]
External Id：P53MS898

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve...
来源：NCGC
靶标：N/A
External Id：OBG420

共266条，当前第1页，共27页