Kallikrein-IN-1

更新时间：2025-08-21 16:43:20

Kallikrein-IN-1用途

激肽释放酶-IN-1(式A)是一种激肽释放酶抑制剂[1]。

英文名	Kallikrein-IN-1

描述	激肽释放酶-IN-1(式A)是一种激肽释放酶抑制剂[1]。
相关类别	信号通路 >> 代谢酶/蛋白酶 >> Ser/Thr蛋白酶研究领域 >> 其他
参考文献	[1]. POLYMORPHS OF N-[6-CYANO-2-FLUORO)-3-METHOXYPHENYL) METHYL]-3-(METHOXYMETHYL)-1-({4-[(2-OXOPYRIDIN-1-YL)METHYL]PHENYL}METHYL)PYRAZOLE-4-CARBOXAMIDE AS KALLIKREIN INHIBITORS. Patent WO2017208002.

分子式	C₂₈H₂₆FN₅O₄
分子量	515.54

实验名称：Volume of distribution at steady state in Sprague-Dawley rat at 10 mg/kg, po and 1 mg...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5112826

实验名称：Half life in Sprague-Dawley rat at 10 mg/kg, po and 1 mg/kg, iv measured upto 24 hrs ...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5112828

实验名称：Clearance in Sprague-Dawley rat blood at 1 mg/kg, iv measured upto 24 hrs by LC-MS an...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5112822

实验名称：Clearance in Sprague-Dawley rat assessed as liver blood flow at 1 mg/kg, iv measured ...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5112824

实验名称：Thermodynamic solubility of the compound in FaSSGF at 1 mg/ml at pH 1.6 measured afte...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5112818

实验名称：Clearance in Sprague-Dawley rat plasma at 1 mg/kg, iv measured upto 24 hrs by LC-MS a...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5112820

实验名称：Kinetic solubility of the compound in aqueous assay buffer at pH 7.7
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5112814

实验名称：Thermodynamic solubility of the compound in FaSSIF at 1 mg/ml at pH 6.5 measured afte...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5112817

实验名称：Metabolic stability in human liver microsomes assessed as intrinsic clearance per mg ...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5112810

实验名称：Inhibitory Activity of Exemplary Compounds against Plasma Kallikrein from US Patent U...
来源：BindingDB
靶标：N/A
External Id：BindingDB_9280_1

共24条，当前第1页，共3页