巴洛沙韦

• 常用名: 巴洛沙韦
• 英文名: Baloxavir
• CAS号: 1985605-59-1
• 分子量: 483.487
• 密度: 1.6±0.1 g/cm3
• 沸点: 644.7±65.0 °C at 760 mmHg
• 分子式: C₂₄H₁₉F₂N₃O₄S
• 熔点: N/A
• 闪点: 343.7±34.3 °C

巴洛沙韦用途

Baloxavir 是一种抗流感病毒药物,来自专利 WO 2017104691 A1。

巴洛沙韦名称

• 中文名: Baloxavir
• 英文名: Baloxavir
• 中文别名: 巴洛沙韦

巴洛沙韦生物活性

• 描述: Baloxavir 是一种抗流感病毒药物,来自专利 WO 2017104691 A1。
• 相关类别:
  信号通路 >> 抗感染 >> 流感病毒
  研究领域 >> 感染
• 靶点实验:

  Influenza virus[1]

• 参考文献:

  [1]. Shishido Takao, et al. Medicine for treating influenza characterized by comprising combination of cap-dependent endonuclease inhibitor with anti-influenza drug. WO 2017104691 A1.

巴洛沙韦物理化学性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 644.7±65.0 °C at 760 mmHg
• 分子式: C₂₄H₁₉F₂N₃O₄S
• 分子量: 483.487
• 闪点: 343.7±34.3 °C
• 精确质量: 483.106445
• LogP: 1.51
• 蒸汽压: 0.0±2.0 mmHg at 25°C
• 折射率: 1.757
• 储存条件: 2-8℃

巴洛沙韦靶点实验

查看更多实验

实验名称：Binding affinity towards rat Gabra1 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-1 External Id：CHEMBL5291800

实验名称：Stability in human liver S9 fraction assessed as parent compound remaining at 1 uM me... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626806

实验名称：Stability in human plasma assessed as parent compound remaining at 1 uM measured afte... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626805

实验名称：Stability in rat liver S9 fraction assessed as parent compound remaining at 1 uM meas... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626808

实验名称：Stability in rat plasma assessed as parent compound remaining at 1 uM measured after ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626807

实验名称：Stability in mouse liver S9 fraction assessed as parent compound remaining at 1 uM me... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626810

实验名称：Stability in mouse plasma assessed as parent compound remaining at 1 uM measured afte... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626809

实验名称：Binding affinity towards human ESR1 in an in vitro cell free assay (CRO assay) measur... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL5291792

实验名称：Compound was evaluated for inhibition of human F2 in an in vitro cell free assay meas... 来源：ChEMBL 靶标：Prothrombin External Id：CHEMBL5291794

实验名称：Anti-influenza activity against Influenza A virus A/PR/8/34 (H1N1) infected in MDCK c... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL5516489

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巴洛沙韦英文别名

• (12aR)-12-[(11S)-7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-7-hydroxy-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione
• 4G86Y4JT3F