西瑞香素

• 常用名: 西瑞香素
• 英文名: Daphnoretin
• CAS号: 2034-69-7
• 分子量: 352.294
• 密度: 1.5±0.1 g/cm3
• 沸点: 639.6±55.0 °C at 760 mmHg
• 分子式: C₁₉H₁₂O₇
• 熔点: 245-246℃
• 闪点: 237.8±25.0 °C

西瑞香素用途

Daphnoretin (Dephnoretin) 是从Wikstroemia indica 中提取得到的,拥有抗病毒活性。Daphnoretin 和PMA作用类似,可以直接激活蛋白激酶C,从而激活NADPH氧化酶。

西瑞香素名称

• 中文名: 西瑞香素
• 英文名: Daphnoretin

西瑞香素生物活性

• 描述: Daphnoretin (Dephnoretin) 是从Wikstroemia indica 中提取得到的,拥有抗病毒活性。Daphnoretin 和PMA作用类似,可以直接激活蛋白激酶C,从而激活NADPH氧化酶。
• 相关类别:
  信号通路 >> 表观遗传学 >> PKC
  研究领域 >> 感染
  信号通路 >> TGF-beta/Smad 信号通路 >> PKC
• 参考文献:

  [1]. Ho WS, et al. Antiviral activity of daphnoretin isolated from Wikstroemia indica. Phytother Res. 2010 May;24(5):657-61.

  [2]. Wang JP, et al. Daphnoretin-induced respiratory burst in rat neutrophils is, probably, mainly through protein kinase C activation. Eur J Pharmacol. 1995 Feb 15;288(3):341-8.

西瑞香素物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 639.6±55.0 °C at 760 mmHg
• 熔点: 245-246℃
• 分子式: C₁₉H₁₂O₇
• 分子量: 352.294
• 闪点: 237.8±25.0 °C
• 精确质量: 352.058289
• PSA: 99.11000
• LogP: 3.33
• InChIKey: JRHMMVBOTXEHGJ-UHFFFAOYSA-N
• SMILES: COc1cc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2cc1O
• 蒸汽压: 0.0±2.0 mmHg at 25°C
• 折射率: 1.675
• 储存条件: 2-8C

西瑞香素毒性和生态

西瑞香素安全信息

• 海关编码: 2932209090

西瑞香素海关

• 海关编码: 2932209090
• 中文概述: 2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

西瑞香素靶点实验

查看更多实验

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实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint... 来源：Broad Institute 靶标：N/A External Id：2084-01_Activator_SinglePoint_HTS_Activity

实验名称：Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberc... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：GDH-TPI_INH_ABS_1536_1X%INH CSRUN

实验名称：Hedgehog Measured in Biochemical System Using Plate Reader - 2070-01_Inhibitor_Single... 来源：Broad Institute 靶标：hedgehog, isoform A [Drosophila melanogaster] External Id：2070-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：qHTS for Inhibitors of TGF-b: Cytotox Counterscreen 来源：NCGC 靶标：N/A External Id：SMAD3201

实验名称：uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay 来源：Burnham Center for Chemical Genomics 靶标：cystic fibrosis transmembrane conductance regulator [Homo sapiens] External Id：SBCCG-A764-CF-PAF-Primary-Assay

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ant... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_ANT_FLUO8_1536_1X%INH PRUN

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西瑞香素英文别名

• 7-hydroxyl-6-methoxy-3,7'-dicoumarylether
• 7-hydroxy-6-methoxy-3,7'-dicoumaryl ether
• Thymelol
• 7-hydroxy-6-methoxy-3-(2-oxochromen-7-yl)oxychromen-2-one
• COUMARIN,7-HYDROXY-6-METHOXY-3,7'-OXYDI
• 6-methoxy-7-hydroxy-3,7'-dicoumaric ether
• Daphnoretin
• 7-Hydroxy-6-methoxy-3-[(2-oxo-2H-chromen-7-yl)oxy]-2H-chromen-2-one