GPR35 agonist 1

• 常用名: GPR35 agonist 1
• 英文名: GPR35 agonist 1
• CAS号: 2079880-92-3
• 分子量: 354.07
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₀H₄BrN₅O₅
• 熔点: N/A
• 闪点: N/A

GPR35 agonist 1用途

GPR35 agonist 1 (compound 50)是一种高效特异性的 GPR35 激动剂,EC50 值为 5.8 nM,具有很好的成药性。

GPR35 agonist 1名称

• 英文名: GPR35 agonist 1

GPR35 agonist 1生物活性

• 描述: GPR35 agonist 1 (compound 50)是一种高效特异性的 GPR35 激动剂,EC50 值为 5.8 nM,具有很好的成药性。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 靶点实验:

  EC50: 5.8 nM (GPR35)[1]

• 参考文献:

  [1]. Wei L, et al. Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists. J Med Chem. 2017 Jan 12;60(1):362-372.

GPR35 agonist 1物理化学性质

• 分子式: C₁₀H₄BrN₅O₅
• 分子量: 354.07
• InChIKey: AQJFPDDDKBWBAG-UHFFFAOYSA-N
• SMILES: O=c1oc2c([N+](=O)[O-])c(O)c(Br)cc2cc1-c1nn[nH]n1

GPR35 agonist 1靶点实验

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实验名称：Agonist activity at GPR109a receptor in human A431 cells at 1 uM preincubated for 1 h... 来源：ChEMBL 靶标：Hydroxycarboxylic acid receptor 2 External Id：CHEMBL4042619

实验名称：Agonist activity at TEV protease cleavage site linked GAL4-VP16-fused GPR35 in human ... 来源：ChEMBL 靶标：G-protein coupled receptor 35 External Id：CHEMBL4042617

实验名称：Agonist activity at GPR35 in human HT-29 cells in presence of antagonist ML-145 by DM... 来源：ChEMBL 靶标：G-protein coupled receptor 35 External Id：CHEMBL4042615

实验名称：Agonist activity at bradykinin B2 receptor in human A549 cells at 1 uM preincubated f... 来源：ChEMBL 靶标：B2 bradykinin receptor External Id：CHEMBL4042622

实验名称：Agonist activity at beta2 adrenergic receptor in human A431 cells at 1 uM preincubate... 来源：ChEMBL 靶标：Beta-2 adrenergic receptor External Id：CHEMBL4042620

实验名称：Agonist activity at angiotensin AT1 receptor in human A549 cells at 1 uM preincubated... 来源：ChEMBL 靶标：Type-1 angiotensin II receptor External Id：CHEMBL4042621

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