4-(苯并[d]恶唑-2-基)苯胺

• 常用名: 4-(苯并[d]恶唑-2-基)苯胺
• 英文名: 4-(BENZO[D]OXAZOL-2-YL)ANILINE
• CAS号: 20934-81-0
• 分子量: 210.23100
• 密度: 1.257g/cm3
• 沸点: 361.4ºC at 760mmHg
• 分子式: C₁₃H₁₀N₂O
• 熔点: N/A
• 闪点: 172.4ºC

4-(苯并[d]恶唑-2-基)苯胺用途

4-(苯并[d]恶唑-2-基)苯胺是一种有效的抗肿瘤剂。4-(苯并[d]恶唑-2-基)苯胺对乳腺癌细胞株具有抑制活性[1]。

4-(苯并[d]恶唑-2-基)苯胺名称

• 中文名: 4-苯并噁唑-2-苯胺
• 英文名: 4-(1,3-benzoxazol-2-yl)aniline

4-(苯并[d]恶唑-2-基)苯胺生物活性

• 描述: 4-(苯并[d]恶唑-2-基)苯胺是一种有效的抗肿瘤剂。4-(苯并[d]恶唑-2-基)苯胺对乳腺癌细胞株具有抑制活性[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 体外研究: 4-(苯并[d]恶唑-2-基)苯胺(化合物5b)(0-100μM；MCF-7为7天,MDA 468为10天)对MCF-7和MDA 468-乳腺癌细胞株具有抑制活性[1]。细胞增殖试验[1]细胞株：MCF-7和MDA 468浓度：0-100μM培养时间：MCF-7d,MDA 468d结果：显示对MCF-7(IC50>0.01-0.1μM)和MDA 4.68(IC50>0.1-1μM)的抑制活性。
• 参考文献:

  [1]. Shi DF, et al. Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo. J Med Chem. 1996 Aug 16;39(17):3375-84.

4-(苯并[d]恶唑-2-基)苯胺物理化学性质

• 密度: 1.257g/cm3
• 沸点: 361.4ºC at 760mmHg
• 分子式: C₁₃H₁₀N₂O
• 分子量: 210.23100
• 闪点: 172.4ºC
• 精确质量: 210.07900
• PSA: 52.05000
• LogP: 3.65820
• InChIKey: XZYQBYQGHHGXBC-UHFFFAOYSA-N
• SMILES: Nc1ccc(-c2nc3ccccc3o2)cc1
• 蒸汽压: 2.08E-05mmHg at 25°C
• 折射率: 1.682
• 储存条件: 室温，避光，干燥，密封

4-(苯并[d]恶唑-2-基)苯胺安全信息

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

4-(苯并[d]恶唑-2-基)苯胺海关

• 海关编码: 2934999090
• 中文概述: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-(苯并[d]恶唑-2-基)苯胺靶点实验

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实验名称：Dicer-mediated maturation of pre-microRNA 来源：Center for Chemical Genomics, University of Michigan 靶标：N/A External Id：TargetID_659_CEMA

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4-(苯并[d]恶唑-2-基)苯胺英文别名

• 4-Benzoxazol-2-ylphenylamine
• 4-Benzooxazol-2-yl-phenylamine