美洲茶酸

• 常用名: 美洲茶酸
• 英文名: Emmolic Acid
• CAS号: 21302-79-4
• 分子量: 486.683
• 密度: 1.1±0.1 g/cm3
• 沸点: 609.0±55.0 °C at 760 mmHg
• 分子式: C₃₀H₄₆O₅
• 熔点: 356-357°
• 闪点: 336.1±28.0 °C

美洲茶酸用途

Ceanothic acid (Emmolic acid) 是桦木酸的同源物。Ceanothic acid 抑制 OVCAR-3,HeLa 和 FS-5 细胞,细胞存活率分别为 68％,65％ 和 81％。

美洲茶酸名称

• 中文名: 美洲茶酸
• 英文名: (1R,2S,3aR,5aR,5bR,7aS,10R,10aR,10bR,12aR,12bR)-2-Hydroxy-10-isop ropenyl-3,3,5a,5b,12b-pentamethyloctadecahydrodicyclopenta[a,i]ph enanthrene-1,7a(1H)-dicarboxylic acid

美洲茶酸生物活性

• 描述: Ceanothic acid (Emmolic acid) 是桦木酸的同源物。Ceanothic acid 抑制 OVCAR-3,HeLa 和 FS-5 细胞,细胞存活率分别为 68％,65％ 和 81％。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Lee SS, et al. Preparation and cytotoxic effect of ceanothic acid derivatives. J Nat Prod. 1998 Nov;61(11):1343-7.

美洲茶酸物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 609.0±55.0 °C at 760 mmHg
• 熔点: 356-357°
• 分子式: C₃₀H₄₆O₅
• 分子量: 486.683
• 闪点: 336.1±28.0 °C
• 精确质量: 486.334534
• PSA: 94.83000
• LogP: 7.24
• InChIKey: WLCHQSHZHFLMJH-VILVJDKQSA-N
• SMILES: C=C(C)C1CCC2(C(=O)O)CCC3(C)C(CCC4C5(C)C(C(=O)O)C(O)C(C)(C)C5CCC43C)C12
• 外观性状: 粉末
• 蒸汽压: 0.0±4.0 mmHg at 25°C
• 折射率: 1.549
• 储存条件: 2-8℃，干燥，密闭

美洲茶酸安全信息

• 危害码 (欧洲): Xi

美洲茶酸靶点实验

查看更多实验

实验名称：Cytotoxicity against human HeLa cells assessed as cell survival after 48 hrs by MTT a... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL995680

实验名称：Cytotoxicity against human FS5 cells assessed as cell survival after 48 hrs by MTT as... 来源：ChEMBL 靶标：N/A External Id：CHEMBL995681

实验名称：Cytotoxicity against human Raji cells assessed as cell viability at 1000 molar ratio ... 来源：ChEMBL 靶标：Raji External Id：CHEMBL951807

实验名称：Antifungal activity against Candida albicans 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL2157591

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL954656

实验名称：Cytotoxicity against human Raji cells assessed as cell viability at 100 molar ratio a... 来源：ChEMBL 靶标：Raji External Id：CHEMBL951809

实验名称：Cytotoxicity against human HeLa cells 来源：ChEMBL 靶标：HeLa External Id：CHEMBL2157589

实验名称：Cytotoxicity against human Raji cells assessed as cell viability at 500 molar ratio a... 来源：ChEMBL 靶标：Raji External Id：CHEMBL951808

实验名称：Antibacterial activity against Staphylococcus aureus 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL2157590

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL954653

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美洲茶酸英文别名

• Emmolic Acid
• (1R,2S,3aR,5aR,5bR,7aS,10R,10aR,10bR,12aR,12bR)-2-Hydroxy-10-isopropenyl-3,3,5a,5b,12b-pentamethyloctadecahydrodicyclopenta[a,i]phenanthrene-1,7a(1H)-dicarboxylic acid
• ceanothic acid
• (2a,3b)-3-Hydroxy-A(1),28-dinorlup-20(29)-ene-2,17-dicarboxylic acid
• 2a-Carboxy-3b-hydroxy-A(1)-norlup-20(29)-en-28-oic Acid
• (1R,2S,3aR,5aR,5bR,7aS,10R,10aR,10bR,12aR,12bR)-2-Hydroxy-3,3,5a,5b,12b-pentamethyl-10-(prop-1-en-2-yl)octadecahydrodicyclopenta[a,i]phenanthrene-1,7a(1H)-dicarboxylic acid