托拉菌素 A

更新时间：2025-08-20 11:00:22

托拉菌素 A结构式	常用名	托拉菌素 A	英文名	Tulathromycin A
	CAS号	217500-96-4	分子量	806.079
	密度	1.2±0.1 g/cm3	沸点	853.8±65.0 °C at 760 mmHg
	分子式	C₄₁H₇₉N₃O₁₂	熔点	N/A
	MSDS	N/A	闪点	470.2±34.3 °C

托拉菌素 A用途

Tulathromycin A 是大环内酯类抗生素,MIC90为1μg/ml。

中文名	托拉菌素 A
英文名	Tulathromycin A
中文别名	土拉霉素A \| 土拉霉素 A \| 泰拉霉素A \| 托拉菌素A \| 泰拉霉素
英文别名	更多

描述	Tulathromycin A 是大环内酯类抗生素,MIC90为1μg/ml。
相关类别	信号通路 >> 抗感染 >> 细菌研究领域 >> 感染
参考文献	[1]. Villarino N, et al. Pharmacokinetics of tulathromycin in healthy and neutropenic mice challenged intranasally withlipopolysaccharide from Escherichia coli. Antimicrob Agents Chemother. 2012 Aug;56(8):4078-4086. [2]. Godinho KS, et al. Efficacy of tulathromycin in the treatment of bovine respiratory disease associated with induced Mycoplasma bovis infections in young dairy calves. Vet Ther. 2005 Summer;6(2):96-112. [3]. Godinho KS, et al. Minimum inhibitory concentrations of tulathromycin against respiratory bacterial pathogens isolated from clinical cases in European cattle and swine and variability arising from changes in in vitro methodology. Vet Ther. 2005 Summer;6(2 [4]. Rooney KA, et al. Efficacy of tulathromycin compared with tilmicosin and florfenicol for the control of respiratory disease in cattle at high risk of developing bovine respiratory disease. Vet Ther. 2005 Summer;6(2):154-66. [5]. Kilgore WR, et al. Therapeutic efficacy of tulathromycin, a novel triamilide antimicrobial, against bovine respiratory disease in feeder calves. Vet Ther. 2005 Summer;6(2):143-53.

描述

Tulathromycin A 是大环内酯类抗生素,MIC90为1μg/ml。

相关类别

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

参考文献

[1]. Villarino N, et al. Pharmacokinetics of tulathromycin in healthy and neutropenic mice challenged intranasally withlipopolysaccharide from Escherichia coli. Antimicrob Agents Chemother. 2012 Aug;56(8):4078-4086.

[2]. Godinho KS, et al. Efficacy of tulathromycin in the treatment of bovine respiratory disease associated with induced Mycoplasma bovis infections in young dairy calves. Vet Ther. 2005 Summer;6(2):96-112.

[3]. Godinho KS, et al. Minimum inhibitory concentrations of tulathromycin against respiratory bacterial pathogens isolated from clinical cases in European cattle and swine and variability arising from changes in in vitro methodology. Vet Ther. 2005 Summer;6(2

[4]. Rooney KA, et al. Efficacy of tulathromycin compared with tilmicosin and florfenicol for the control of respiratory disease in cattle at high risk of developing bovine respiratory disease. Vet Ther. 2005 Summer;6(2):154-66.

[5]. Kilgore WR, et al. Therapeutic efficacy of tulathromycin, a novel triamilide antimicrobial, against bovine respiratory disease in feeder calves. Vet Ther. 2005 Summer;6(2):143-53.

密度	1.2±0.1 g/cm3
沸点	853.8±65.0 °C at 760 mmHg
分子式	C₄₁H₇₉N₃O₁₂
分子量	806.079
闪点	470.2±34.3 °C
精确质量	805.566345
PSA	200.90000
LogP	4.07
InChIKey	GUARTUJKFNAVIK-QPTWMBCESA-N
SMILES	CCCNCC1(O)C(C)OC(OC2C(C)C(=O)OC(CC)C(C)(O)C(O)C(C)NCC(C)CC(C)(O)C(OC3OC(C)CC(N(C)C)C3O)C2C)CC1(C)OC
外观性状	粉末
蒸汽压	0.0±0.6 mmHg at 25°C
折射率	1.536
储存条件	-20℃

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-Dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-a-L-ribo-hexopyranosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one

Tulathromycin

Draxxin

Unii-897A3kn7ap