p38 MAP激酶抑制剂

• 常用名: p38 MAP激酶抑制剂
• 英文名: p38 MAPK-IN-4
• CAS号: 219138-24-6
• 分子量: 365.78800
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₃ClFN₃O
• 熔点: N/A
• 闪点: N/A

p38 MAP激酶抑制剂用途

p38 MAPK-IN-4(化合物6)是一种p38 MAPK抑制剂,其50为35nM[1]。

p38 MAP激酶抑制剂名称

• 中文名: p38 MAP激酶抑制剂
• 英文名: 2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1,2-dihydro -3H-pyrazol-3-one

p38 MAP激酶抑制剂生物活性

• 描述: p38 MAPK-IN-4(化合物6)是一种p38 MAPK抑制剂,其50为35nM[1]。
• 相关类别:
  信号通路 >> MAPK/ERK信号通路 >> p38 MAPK
  研究领域 >> 炎症/免疫
• 靶点实验:

  p38:35 nM (IC50)

• 参考文献:

  [1]. S E de Laszlo, et al. Pyrroles and other heterocycles as inhibitors of p38 kinase. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2689-94.

p38 MAP激酶抑制剂物理化学性质

• 分子式: C₂₀H₁₃ClFN₃O
• 分子量: 365.78800
• 精确质量: 365.07300
• PSA: 50.68000
• LogP: 4.68710
• InChIKey: DZFBYHUKZSRPHU-UHFFFAOYSA-N
• SMILES: O=c1c(-c2ccc(F)cc2)c(-c2ccncc2)[nH]n1-c1ccc(Cl)cc1
• 储存条件: -20°C，密闭，干燥

p38 MAP激酶抑制剂靶点实验

查看更多实验

实验名称：Delta TM value showing the stabilisation of CAMK2G produced by compound binding 来源：ChEMBL 靶标：Calcium/calmodulin-dependent protein kinase type II subunit gamma External Id：CHEMBL3430795

实验名称：Delta TM value showing the stabilisation of CAMK4 produced by compound binding 来源：ChEMBL 靶标：Calcium/calmodulin-dependent protein kinase type IV External Id：CHEMBL3430796

实验名称：Delta TM value showing the stabilisation of CAMK2B produced by compound binding 来源：ChEMBL 靶标：Calcium/calmodulin-dependent protein kinase type II subunit beta External Id：CHEMBL3430793

实验名称：Delta TM value showing the stabilisation of CAMK2D produced by compound binding 来源：ChEMBL 靶标：Calcium/calmodulin-dependent protein kinase type II subunit delta External Id：CHEMBL3430794

实验名称：Delta TM value showing the stabilisation of CDK6 produced by compound binding 来源：ChEMBL 靶标：Cyclin-dependent kinase 6 External Id：CHEMBL3430799

实验名称：Delta TM value showing the stabilisation of CDKL1 produced by compound binding 来源：ChEMBL 靶标：Cyclin-dependent kinase-like 1 External Id：CHEMBL3430800

实验名称：Delta TM value showing the stabilisation of CAMKK2 produced by compound binding 来源：ChEMBL 靶标：Calcium/calmodulin-dependent protein kinase kinase 2 External Id：CHEMBL3430797

实验名称：Delta TM value showing the stabilisation of CDK2 produced by compound binding 来源：ChEMBL 靶标：Cyclin-dependent kinase 2 External Id：CHEMBL3430798

实验名称：Delta TM value showing the stabilisation of CLK2 produced by compound binding 来源：ChEMBL 靶标：Dual specificity protein kinase CLK2 External Id：CHEMBL3430803

实验名称：Delta TM value showing the stabilisation of CLK3 produced by compound binding 来源：ChEMBL 靶标：Dual specificity protein kinase CLK3 External Id：CHEMBL3430804

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