TLR7/8-IN-1

• 常用名: TLR7/8-IN-1
• 英文名: TLR7/8-IN-1
• CAS号: 2205095-75-4
• 分子量: 532.68
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₄₀N₈O₂
• 熔点: N/A
• 闪点: N/A

TLR7/8-IN-1用途

TLR7/8-IN-1是从专利WO2019220390化合物2b中提取的TLR7/TLR8抑制剂的结晶体。TLR7/8-IN-1可用于自身免疫性疾病的研究[1]。

TLR7/8-IN-1名称

• 英文名: TLR7/8-IN-1

TLR7/8-IN-1生物活性

• 描述: TLR7/8-IN-1是从专利WO2019220390化合物2b中提取的TLR7/TLR8抑制剂的结晶体。TLR7/8-IN-1可用于自身免疫性疾病的研究[1]。
• 相关类别:
  信号通路 >> 免疫及炎症 >> Toll样受体(TLR)
  研究领域 >> 炎症/免疫
• 靶点实验:

  TLR7

  TLR8

• 体外研究: TLR7/8-IN-1是TLR7/TLR8抑制剂的结晶体。TLR7/8-IN-1可用于自身免疫性疾病的研究[1]。
• 参考文献:

  [1]. WO2019220390

TLR7/8-IN-1物理化学性质

• 分子式: C₂₉H₄₀N₈O₂
• 分子量: 532.68
• InChIKey: OXDQXRVWDYGAHX-SAVAPUMLSA-N
• SMILES: Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)C5COCCN5)(CC3)CC4)C2)c2cnn(C)c2n1
• 储存条件: -20°C

TLR7/8-IN-1靶点实验

查看更多实验

实验名称：Volume of distribution at steady state in mouse at 1 mg/ml, po or iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL5365118

实验名称：AUC in mouse at 1 mg/ml, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL5365119

实验名称：Clearance in mouse at 1 mg/ml, po or iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL5365117

实验名称：In vivo antagonist activity against TLR4 in mouse assessed as inhibition of IL-6 leve... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5365176

实验名称：In vivo antagonist activity against TLR4 in mouse assessed as inhibition of TNF level... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5365177

实验名称：In vivo antagonist activity against TLR4 in mouse assessed as suppression of IFN alph... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5365174

实验名称：In vivo antagonist activity against TLR4 in mouse assessed as inhibition of IFN alpha... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5365175

实验名称：In vivo antagonist activity against TLR4 in mouse assessed as suppression of IFN alph... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5365172

实验名称：In vivo antagonist activity against TLR4 in mouse assessed as suppression of IFN alph... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5365173

实验名称：In vivo antagonist activity against TLR4 in po dosed mouse assessed as suppression of... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5365170

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