DAA-1106

• 常用名: DAA-1106
• 英文名: DAA-1106
• CAS号: 220551-92-8
• 分子量: 395.42300
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₂FNO₄
• 熔点: N/A
• 闪点: N/A

DAA-1106用途

DAA1106是一种外周苯二氮受体(PBR)激动剂,但对GABAA受体无亲和力。

DAA-1106名称

• 中文名: N-(2,5-二甲氧基苄基)-N-(5-氟-2-苯氧基苯基)乙酰胺
• 英文名: N-[(2,5-dimethoxyphenyl)methyl]-N-(5-fluoro-2-phenoxyphenyl)acetamide

DAA-1106生物活性

• 描述: DAA1106是一种外周苯二氮受体(PBR)激动剂,但对GABAA受体无亲和力。
• 相关类别:
  信号通路 >> 跨膜转运 >> GABA受体
  信号通路 >> 神经信号通路 >> GABA受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Yasuno F, et al. Increased binding of peripheral benzodiazepine receptor in mild cognitive impairment-dementia converters measured by positron emission tomography with [11C]DAA1106. Psychiatry Res. 2012 Jul 30;203(1):67-74.

  [2]. DAA1106

DAA-1106物理化学性质

• 分子式: C₂₃H₂₂FNO₄
• 分子量: 395.42300
• 精确质量: 395.15300
• PSA: 48.00000
• LogP: 5.18830
• InChIKey: DCRZYADKQRHHSF-UHFFFAOYSA-N
• SMILES: COc1ccc(OC)c(CN(C(C)=O)c2cc(F)ccc2Oc2ccccc2)c1
• 储存条件: 2-8℃

DAA-1106靶点实验

查看更多实验

实验名称：Displacement of [125I]N-(5-fluoro-2-phenoxyphenyl)-N-(2-iodo-5-methoxybenzyl)acetamid... 来源：ChEMBL 靶标：Translocator protein External Id：CHEMBL908530

实验名称：Displacement of [3H]PK11195 from TSPO in Wistar rat heart incubated for 15 mins 来源：ChEMBL 靶标：Translocator protein External Id：CHEMBL2071915

实验名称：Displacement of [125I]N-(5-fluoro-2-phenoxyphenyl)-N-(2-iodo-5-methoxybenzyl)acetamid... 来源：ChEMBL 靶标：Translocator protein External Id：CHEMBL908531

实验名称：Decrease in uptake in iv dosed Sprague-Dawley rat brain cerebellum after 30 mins per ... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL859967

实验名称：Partition coefficient (logP) 来源：ChEMBL 靶标：N/A External Id：CHEMBL628298

实验名称：Displacement of [125I]N-(5-fluoro-2-phenoxyphenyl)-N-(2-iodo-5-methoxybenzyl)acetamid... 来源：ChEMBL 靶标：Translocator protein External Id：CHEMBL908536

实验名称：Displacement of [125I]N-(5-fluoro-2-phenoxyphenyl)-N-(2-iodo-5-methoxybenzyl)acetamid... 来源：ChEMBL 靶标：Translocator protein External Id：CHEMBL908537

实验名称：Displacement of [125I]N-(5-fluoro-2-phenoxyphenyl)-N-(2-iodo-5-methoxybenzyl)acetamid... 来源：ChEMBL 靶标：Translocator protein External Id：CHEMBL908538

实验名称：Displacement of [125I]N-(5-fluoro-2-phenoxyphenyl)-N-(2-iodo-5-methoxybenzyl)acetamid... 来源：ChEMBL 靶标：Translocator protein External Id：CHEMBL907391

实验名称：Displacement of [125I]N-(5-fluoro-2-phenoxyphenyl)-N-(2-iodo-5-methoxybenzyl)acetamid... 来源：ChEMBL 靶标：Translocator protein External Id：CHEMBL908532

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DAA-1106英文别名

• N-[(2,5-dimethoxyphenyl)methyl]-N-(5-fluoranyl-2-phenoxyphenyl)acetamide
• DAA-1106
• DAA1106