Neuraminidase-IN-9

• 常用名: Neuraminidase-IN-9
• 英文名: Neuraminidase-IN-9
• CAS号: 2217630-64-1
• 分子量: 533.46
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₃₃BrN₆O₃
• 熔点: N/A
• 闪点: N/A

Neuraminidase-IN-9用途

神经氨酸酶-IN-9(化合物6l)是一种有效的流感神经氨酸酶抑制剂,对H5N1、H5N2和H5N6的IC50值分别为0.12、0.049和0.16µM【1】。

Neuraminidase-IN-9名称

• 英文名: Neuraminidase-IN-9

Neuraminidase-IN-9生物活性

• 描述: 神经氨酸酶-IN-9(化合物6l)是一种有效的流感神经氨酸酶抑制剂,对H5N1、H5N2和H5N6的IC50值分别为0.12、0.049和0.16µM【1】。
• 相关类别:
  信号通路 >> 抗感染 >> 流感病毒
  研究领域 >> 感染
• 靶点实验:

  IC50: 0.049 µM (H5N2), 0.12 µM (H5N1), 0.16 µM (H5N6)[1] EC50: 0.43 µM (H5N2), 2.45 µM (H5N1), 2.8 µM (H5N6)[1]

• 参考文献:

  [1]. Ju H, et al. Discovery of novel 1,2,3-triazole oseltamivir derivatives as potent influenza neuraminidase inhibitors targeting the 430-cavity. Eur J Med Chem. 2020 Feb 1;187:111940.

Neuraminidase-IN-9物理化学性质

• 分子式: C₂₄H₃₃BrN₆O₃
• 分子量: 533.46

Neuraminidase-IN-9靶点实验

查看更多实验

实验名称：Inhibition of Influenza A virus H5N1 Neuraminidase N1 H274Y mutant preincubated for 1... 来源：ChEMBL 靶标：Neuraminidase External Id：CHEMBL4403917

实验名称：Selectivity index, ratio of CC50 for CEF to EC50 for Influenza A virus (A/goose/Guang... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4403923

实验名称：Antiviral activity against Influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) infecte... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL4403924

实验名称：Antiviral activity against Influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) infecte... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL4403925

实验名称：Antiviral activity against Influenza A virus (A/Chicken/China/415/2013 (H9N2)) infect... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL4403926

实验名称：Inhibition of Influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 p... 来源：ChEMBL 靶标：Neuraminidase External Id：CHEMBL4403914

实验名称：Inhibition of Influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 pre... 来源：ChEMBL 靶标：Neuraminidase External Id：CHEMBL4403915

实验名称：Inhibition of Influenza A virus (A/Duck/Guangdong/674/2014(H5N6)) Neuraminidase N6 pr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4403916

共8条，当前第1页，共1页

1