IZCZ-3

• 常用名: IZCZ-3
• 英文名: IZCZ-3
• CAS号: 2223019-53-0
• 分子量: 715.93
• 密度: N/A
• 沸点: N/A
• 分子式: C₄₆H₄₉N₇O
• 熔点: N/A
• 闪点: N/A

IZCZ-3用途

IZCZ-3是有效的c-MYC 转录抑制剂,具有抗肿瘤活性。

IZCZ-3名称

• 中文名: IZCZ-3
• 英文名: IZCZ-3

IZCZ-3生物活性

• 描述: IZCZ-3是有效的c-MYC 转录抑制剂,具有抗肿瘤活性。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞凋亡 >> c-Myc的
• 参考文献:

  [1]. Hu MH, et al. Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c-MYC Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex. J Med Chem. 2018 Mar 22;61(6):2447-2459.

IZCZ-3物理化学性质

• 分子式: C₄₆H₄₉N₇O
• 分子量: 715.93

IZCZ-3靶点实验

查看更多实验

实验名称：Stabilization of c-Myc mutant promoter DNA (unknown origin) transfected in human SiHa... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4037752

实验名称：Stabilization of c-Myc promoter G-quadruplex DNA in human Raji cells assessed as down... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4037753

实验名称：Stabilization of KRAS promoter G-quadruplex DNA (unknown origin) assessed as effect o... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4037750

实验名称：Stabilization of wild type c-Myc promoter G-quadruplex DNA (unknown origin) transfect... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4037751

实验名称：Stabilization of c-Kit1 promoter G-quadruplex DNA (unknown origin) assessed as effect... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4037748

实验名称：Stabilization of BCL2 promoter G-quadruplex DNA (unknown origin) assessed as effect o... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4037749

实验名称：Stabilization of c-Myc promoter pu22 G-quadruplex DNA (unknown origin) assessed as ch... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4037746

实验名称：Stabilization of antiparallel HRAS G-quadruplex DNA (unknown origin) assessed as effe... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4037747

实验名称：Cytotoxicity against human A375 cells assessed as reduction in cell viability after 2... 来源：ChEMBL 靶标：A-375 External Id：CHEMBL4037760

实验名称：Cytotoxicity against mouse primary mesangial cells assessed as reduction in cell viab... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4037761

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