BAY-6672

更新时间：2025-08-25 08:39:53

BAY-6672用途

BAY-6672是一种有效的选择性人前列腺素F(FP)受体拮抗剂,IC50值为11 nM。

英文名	BAY-6672

描述	BAY-6672是一种有效的选择性人前列腺素F(FP)受体拮抗剂,IC50值为11 nM。
相关类别	研究领域 >> 其他信号通路 >> G 蛋白偶联受体/G 蛋白 >> 前列腺素受体
参考文献	[1]. Beck H, et al. Potent and Selective Human Prostaglandin F (FP) Receptor Antagonist (BAY-6672) for the Treatment of Idiopathic Pulmonary Fibrosis (IPF). J Med Chem. 2020 Oct 22;63(20):11639-11662.

分子式	C₂₆H₂₇BrClN₃O₃
分子量	544.87

实验名称：Thermal Shift Assay. Domain start/stop: M626-G740
来源：ChEMBL
靶标：Peregrin
External Id：CHEMBL4650107

实验名称：Thermal Shift Assay. Domain: start/stop: M1-L298
来源：ChEMBL
靶标：Cyclin-dependent kinase 2
External Id：CHEMBL5062802

实验名称：Cell viability screening matched tumor and healthy colorectal patient-derived organoi...
来源：ChEMBL
靶标：Colon organoid
External Id：CHEMBL5724804

实验名称：Oral bioavailability in Wistar rat at 1 to 3 mg/kg administered via gavage using EtOH...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4671503

实验名称：Antifibrotic activity in silica-induced pulmonary fibrosis C57Bl6J mouse model assess...
来源：ChEMBL
靶标：Mus musculus
External Id：CHEMBL4671489

实验名称：Solubility of compound in water using crystalline form of sample
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4671488

实验名称：Antifibrotic activity in silica-induced pulmonary fibrosis C57Bl6J mouse model assess...
来源：ChEMBL
靶标：Mus musculus
External Id：CHEMBL4671491

实验名称：Antifibrotic activity in silica-induced pulmonary fibrosis C57Bl6J mouse model assess...
来源：ChEMBL
靶标：Mus musculus
External Id：CHEMBL4671490

实验名称：Solubility of compound in 0.1 M HCl using crystalline form of sample
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4671487

实验名称：Solubility of compound in phosphate buffer at pH 8 using crystalline form of sample
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4671486

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