FtsZ-IN-2

• 常用名: FtsZ-IN-2
• 英文名: FtsZ-IN-2
• CAS号: 2249757-45-5
• 分子量: 497.70
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₀H₃₅N₅S
• 熔点: N/A
• 闪点: N/A

FtsZ-IN-2用途

FtsZ-IN-2(化合物19)是细菌细胞分裂蛋白FtsZ的抑制剂,具有GTPase抑制活性。FtsZ-IN-2具有抗葡萄球菌活性,MSSA和MRSA的MIC值为2µg/ml【1】。

FtsZ-IN-2名称

• 英文名: FtsZ-IN-2

FtsZ-IN-2生物活性

• 描述: FtsZ-IN-2(化合物19)是细菌细胞分裂蛋白FtsZ的抑制剂,具有GTPase抑制活性。FtsZ-IN-2具有抗葡萄球菌活性,MSSA和MRSA的MIC值为2µg/ml【1】。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Buroni S, et al. The cell division protein FtsZ as a cellular target to hit cystic fibrosis pathogens. Eur J Med Chem. 2020 Mar 15;190:112132.

FtsZ-IN-2物理化学性质

• 分子式: C₃₀H₃₅N₅S
• 分子量: 497.70

FtsZ-IN-2靶点实验

查看更多实验

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实验名称：Potency index, ratio of methicillin MIC to test compound MIC for methicillin-resistan... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4326858

实验名称：Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 700221... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL4326857

实验名称：Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 ... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL4326856

实验名称：Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4326855

实验名称：Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33592... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4326854

实验名称：Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4326853

实验名称：Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 77... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4326868

实验名称：Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 72... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4326867

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