诃子鞣酸

更新时间：2024-01-04 23:09:18

诃子鞣酸结构式	常用名	诃子鞣酸	英文名	Chebulagic acid
	CAS号	23094-71-5	分子量	954.661
	密度	2.1±0.1 g/cm3	沸点	1610.6±65.0 °C at 760 mmHg
	分子式	C₄₁H₃₀O₂₇	熔点	>300℃
	MSDS	中文版美版	闪点	480.0±27.8 °C

诃子鞣酸用途

Chebulagic acid是一个从果实中提取出来的COX-LOX双重抑制剂。有抗炎和抗感染的效果。

中文名	诃子鞣质
英文名	1-O-galloyl-2,4-O-chebuloyl-3,6-O-HHDP-β-D-glucose
中文别名	诃子鞣酸
英文别名	更多

描述	Chebulagic acid是一个从果实中提取出来的COX-LOX双重抑制剂。有抗炎和抗感染的效果。
相关类别	信号通路 >> 其他 >> 其他研究领域 >> 炎症/免疫天然产物 >> 酚类
参考文献	[1]. Kim HJ et al. Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells. Biomol Ther (Seoul). 2014 Jul;22(4):275-81. [2]. Liu Y et al. Chebulagic acid inhibits the LPS-induced expression of TNF-α and IL-1β in endothelial cells by suppressing MAPK activation. Exp Ther Med. 2015 Jul;10(1):263-268. [3]. Athira AP et al. Inhibition of Angiogenesis In Vitro by Chebulagic Acid: A COX-LOX Dual Inhibitor. Int J Vasc Med. 2013;2013:843897.

描述

Chebulagic acid是一个从果实中提取出来的COX-LOX双重抑制剂。有抗炎和抗感染的效果。

相关类别

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

天然产物 >> 酚类

参考文献

[1]. Kim HJ et al. Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells. Biomol Ther (Seoul). 2014 Jul;22(4):275-81.

[2]. Liu Y et al. Chebulagic acid inhibits the LPS-induced expression of TNF-α and IL-1β in endothelial cells by suppressing MAPK activation. Exp Ther Med. 2015 Jul;10(1):263-268.

[3]. Athira AP et al. Inhibition of Angiogenesis In Vitro by Chebulagic Acid: A COX-LOX Dual Inhibitor. Int J Vasc Med. 2013;2013:843897.

密度	2.1±0.1 g/cm3
沸点	1610.6±65.0 °C at 760 mmHg
熔点	>300℃
分子式	C₄₁H₃₀O₂₇
分子量	954.661
闪点	480.0±27.8 °C
精确质量	954.097473
PSA	447.09000
LogP	2.25
蒸汽压	0.0±0.3 mmHg at 25°C
折射率	1.876
储存条件	-20°C

危险品运输编码	NONH for all modes of transport

诃子鞣酸上游产品 0
诃子鞣酸下游产品 1
CAS号1707-75-1 1,1-二苯基-2-苦味酰肼

Chemical changes during fermentation of Abhayarishta and its standardization by HPLC-DAD.

Nat. Prod. Commun. 5(4) , 575-9, (2010)

Abhayarishta is an Ayurvedic formulation prepared traditionally by the fermentation of the decoction of Terminalia chebula (pericarp), Vitis vinifera (fruits), Embelia ribes (fruits) and Madhuca indic...

[Analysis of tannins in Fructus Chebulae and its confusion varieties by HPCE].

Yao Xue Xue Bao 36(4) , 292-5, (2001)

To analyze the hydrolyzable tannins-chebulinic acid (I) and chebulagic acid(II) in Fructus Chebulae and its confusion varieties by using high performance capillary electrophoresis (HPCE) method.Using ...

[Assay of three hydrolyzable tannins in Fructus Chebulae from different habitats by RP-HPLC].

Zhong Yao Cai 23(6) , 328-30, (2000)

Three hydrolyzable tannins chebulinic acid (I), chebulagic acid(II) and 1,3, 6-tri-O-galloyl-beta-D-glucose (III) in Fructus Chebulae from different habitats were determined by RP-HPLC method. The con...

Chebulagic acid

[(4R,5S,7R,25S,26R,29S,30S,31S)-13,14,15,18,19,20,31,35,36-Nonahydroxy-2,10,23,28,32-pentaoxo-5-[(3,4,5-trihydroxybenzoyl)oxy]-3,6,9,24,27,33-hexaoxaheptacyclo[28.7.1.0.0.0.0 .0]octatriaconta-1(38),11,13,15,17,19,21,34,36-nonaen-29-yl]acetic acid

10,24-(Epoxymethano)-11H-4,9,12,23,25-pentaoxadibenzo[5',6':7',8']cyclododeca[1',2':7,8]cycloundeca[1,2,3-de]naphthalene-7-acetic acid, 5,6,6a,7,8,9a,10,13,22,23a,24,26-dodecahydro-2,3,6,15,16,17,18,19,20-nonahydroxy-5,8,13,22,26-pentaoxo-27-[(3,4,5-trihydroxybenzoyl)oxy]-, (6S,6aS,7S,9aR,10R,23aS,24R,27S)-

CHEBULAGIC ACID(RG)